IHC (Immunohiostchemistry)
(Formalin-fixed, paraffin-embedded human tonsil stained with AKR1C1 Mouse Monoclonal Antibody (CPTC-AKR1C1-2).)
Mouse anti-Human Aldo-keto Reductase Family 1 Member C1/DD1 Monoclonal Antibody | anti-AKR1C1 antibody
Aldo-keto Reductase Family 1 Member C1/DD1
Gene Names
AKR1C1; C9; DD1; DDH; DDH1; H-37; HBAB; MBAB; HAKRC; DD1/DD2; 2-ALPHA-HSD; 20-ALPHA-HSD
Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Purity
Purified Ab with BSA and Azide at 200ug/ml or Purified Ab with BSA and Azide at 200ug/ml or Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Synonyms
Aldo-keto Reductase Family 1 Member C1/DD1, Antibody; Aldo-keto Reductase Family 1 Member C1/DD1; 2-dihydrobenzene-1; 2-diol dehydrogenase; 20 alpha (3 alpha) hydroxysteroid dehydrogenase; 20ALPHAHSD; 2ALPHAHSD; AK1C1; C9; Chlordecone reductase homolog HAKRC; DD1/DD2; DDH1; Dihydrodiol dehydrogenase 1/2; H37; HBAB; Hepatic dihydrodiol dehydrogenase; High affinity hepatic bile acid-binding protein; Indanol dehydrogenase; MBAB; Trans-1; 2 dihydrobenzene 1; 2 diol dehydrogenase; Type II 3 alpha hydroxysteroid dehydrogenase; anti-AKR1C1 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1, kappa
Clone Number
CPTC-AKR1C1-2
Specificity
DDH/AKR1C1 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone.
Purity/Purification
Purified Ab with BSA and Azide at 200ug/ml or Purified Ab with BSA and Azide at 200ug/ml or Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Sequence Length
323
Applicable Applications for anti-AKR1C1 antibody
WB (Western Blot), IHC (Immunohistochemistry)
Immunogen
Recombinant Human full-length AKR1C1 protein
Cellular Localization
Cytoplasm
Hu-chromosome Location
10p15.1
Positive Control
HepG2 or A549 cells. Human liver or Stomach tissue.
Preparation and Storage
Antibody with azide: store at 2 to 8 degree C.
Antibody without azide: store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Antibody without azide: store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
IHC (Immunohiostchemistry)
(Formalin-fixed, paraffin-embedded human tonsil stained with AKR1C1 Mouse Monoclonal Antibody (CPTC-AKR1C1-2).)
IHC (Immunohiostchemistry)
(Formalin-fixed, paraffin-embedded human tonsil stained with AKR1C1 Mouse Monoclonal Antibody (CPTC-AKR1C1-2).)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human tonsil stained with AKR1C1 Mouse Monoclonal Antibody (CPTC-AKR1C1-2).)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human tonsil stained with AKR1C1 Mouse Monoclonal Antibody (CPTC-AKR1C1-2).)
References
Binstock, J.M., et al. 1992. Human hepatic 3-hydroxysteroid dehydrogenase: possible identity with human hepatic chlordecone reductase. Biochem. Biophys. Res. Commun. 187: 760-766.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
37kDa
NCBI Official Full Name
aldo-keto reductase family 1 member C1
NCBI Official Synonym Full Names
aldo-keto reductase family 1 member C1
NCBI Official Symbol
AKR1C1
NCBI Official Synonym Symbols
C9; DD1; DDH; DDH1; H-37; HBAB; MBAB; HAKRC; DD1/DD2; 2-ALPHA-HSD; 20-ALPHA-HSD
NCBI Protein Information
aldo-keto reductase family 1 member C1
UniProt Protein Name
Aldo-keto reductase family 1 member C1
UniProt Gene Name
AKR1C1
UniProt Synonym Gene Names
DDH; DDH1; 20-alpha-HSD; DD1/DD2; HBAB
UniProt Entry Name
AK1C1_HUMAN
Similar Products
Product Notes
The AKR1C1 akr1c1 (Catalog #AAA215371) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Aldo-keto Reductase Family 1 Member C1/DD1 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Aldo-keto Reductase Family 1 Member C1/DD1 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the AKR1C1 akr1c1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Aldo-keto Reductase Family 1 Member C1/DD1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.