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ICC (Immunocytochemistry)
(ICC staining Alpha B Crystallin in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)
Rabbit anti-Human, Rat Alpha B Crystallin Monoclonal Antibody | anti-CRYAB antibody
Alpha B Crystallin Antibody
Gene Names
CRYAB; CRYA2; CTPP2; HSPB5; CMD1II
Reactivity
Human, Rat
Applications
Immunoprecipitation, Immunofluorescence, Immunocytochemistry, Immunohistochemistry, Western Blot
Purity
ProA affinity purified
Synonyms
Alpha B Crystallin, Antibody; Alpha B Crystallin Antibody; AACRYA antibody; Alpha B crystallin antibody; Alpha crystallin B chain antibody; Alpha (B)-crystallin antibody; Alpha-crystallin B chain antibody; CRYA2 antibody; Cryab antibody; CRYAB_HUMAN antibody; Crystallin alpha B antibody; Crystallin alpha polypeptide 2 antibody; CTPP2 antibody; Heat shock 20 kD like protein antibody; Heat shock protein beta 5 antibody; Heat shock protein beta-5 antibody; HspB5 antibody; Renal carcinoma antigen NY REN 27 antibody; Renal carcinoma antigen NY-REN-27 antibody; Rosenthal fiber component antibody; anti-CRYAB antibody
Host
Rabbit
Reactivity
Human, Rat
Clonality
Monoclonal
Clone Number
JA50-32
Purity/Purification
ProA affinity purified
Form/Format
1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Applicable Applications for anti-CRYAB antibody
IP (Immunoprecipitation), IF (Immunofluorescence), ICC (Immunocytochemistry), IHC (Immunohistochemistry), WB (Western Blot)
Antibody Type
Recombinant Antibody
Immunogen
Recombinant protein
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C.
ICC (Immunocytochemistry)
(ICC staining Alpha B Crystallin in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)
ICC (Immunocytochemistry)
(ICC staining Alpha B Crystallin in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)
IHC (Immunohistochemisry)
(Immunohistochemical analysis of paraffin-embedded human prostate tissue using anti-Alpha B Crystallin antibody. Counter stained with hematoxylin.)
IHC (Immunohistochemisry)
(Immunohistochemical analysis of paraffin-embedded human prostate tissue using anti-Alpha B Crystallin antibody. Counter stained with hematoxylin.)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human embryonic skeletal muscle tissue using anti-Alpha B Crystallin antibody. Counter stained with hematoxylin.)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human embryonic skeletal muscle tissue using anti-Alpha B Crystallin antibody. Counter stained with hematoxylin.)
WB (Western Blot)
(Western blot analysis of Alpha B Crystallin on human skeleton musle (1) and mouse heart (2) tissues lysate using anti-Alpha B Crystallin antibody at 1/1, 000 dilution.)
WB (Western Blot)
(Western blot analysis of Alpha B Crystallin on human skeleton musle (1) and mouse heart (2) tissues lysate using anti-Alpha B Crystallin antibody at 1/1, 000 dilution.)
Related Product Information for anti-CRYAB antibody
Crystallins are the major proteins of the vertebrate eye lens, where they maintain the transparency and refractive index of the lens. Crystallins are divided into alpha, beta and gamma families, and the beta- and gamma-crystallins also compose a superfamily. Crystallins usually contain seven distinct protein regions, inclu-ding four homologous motifs, a connecting peptide, and N- and C-terminal extensions. alpha-crystallins consist of three gene products, alphaA-, alphaB- and alphaC-crystallin, which are members of the small heat shock protein family (HSP 20). alpha-crystallins act as molecular chaperones by holding denatured proteins in large soluble aggregates. However, unlike other molecular chaperones, alpha-crystallins do not renature these proteins. Expression of alphaA-crystallin is restricted to the lens and defects of this gene cause the development of autosomal dominant congenital cataracts (ADCC). The human alphaB-crystallin gene product is expressed in many tissues, including lens, heart and skeletal muscle. Elevated expression of alphaB-crystallin is associated with many neurological diseases, and a missense mutation in this gene has co-segregated in a family with a Desmin-related myopathy.
Product Categories/Family for anti-CRYAB antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
20,159 Da
NCBI Official Full Name
alpha-crystallin B chain
NCBI Official Synonym Full Names
crystallin, alpha B
NCBI Official Symbol
CRYAB
NCBI Official Synonym Symbols
CRYA2; CTPP2; HSPB5; CMD1II
NCBI Protein Information
alpha-crystallin B chain; heat shock protein beta-5; rosenthal fiber component; heat-shock 20 kD like-protein; renal carcinoma antigen NY-REN-27
UniProt Protein Name
Alpha-crystallin B chain
UniProt Gene Name
CRYAB
UniProt Synonym Gene Names
CRYA2; HspB5
UniProt Entry Name
CRYAB_HUMAN
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Product Notes
The CRYAB cryab (Catalog #AAA312507) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Alpha B Crystallin Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Alpha B Crystallin can be used in a range of immunoassay formats including, but not limited to, IP (Immunoprecipitation), IF (Immunofluorescence), ICC (Immunocytochemistry), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the CRYAB cryab for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Alpha B Crystallin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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