SDS-PAGE
(SDS PAGE for Amatuximab)
Chimeric anti-Human Amatuximab Monoclonal Antibody | anti-MSLN antibody
Research Grade Amatuximab
Gene Names
MSLN; MPF; SMRP
Reactivity
Human
Purity
>95%Protein A or G purified from cell culture supernatant.
Synonyms
Amatuximab, Antibody; Research Grade Amatuximab; MORAb-009; CAK1 antigen; Mesothelin; MSLN; Pre-pro-megakaryocyte-potentiating factor; MPF; anti-MSLN antibody
Host
Chimeric
Reactivity
Human
Clonality
Monoclonal
Isotype
Human IgG1-kappa
Purity/Purification
>95%
Protein A or G purified from cell culture supernatant.
Protein A or G purified from cell culture supernatant.
Form/Format
Liquid
Concentration
1. 77 mg/ml (varies by lot)
Storage Buffer
PBS buffer, pH7.4
Expression System
XtenCHO
Target
CAK1 antigen, Mesothelin, MSLN, Pre- pro-megakaryocyte-potentiating factor, MPF.
CAS
931402-35-6
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
SDS-PAGE
(SDS PAGE for Amatuximab)
SDS-PAGE
(SDS PAGE for Amatuximab)
Product Categories/Family for anti-MSLN antibody
References
Mesothelin Immunotherapy for Cancer: Ready for Prime Time?, PMID: 27863199
CA125 suppresses amatuximab immune-effector function and elevated serum levels are associated with reduced clinical response in first line mesothelioma patients, PMID: 29652548
Population pharmacokinetics and exposure-response relationship of amatuximab, an anti-mesothelin monoclonal antibody, in patients with malignant pleural mesothelioma and its application in dose selection, PMID: 26898299
Safety and biodistribution of 111In-amatuximab in patients with mesothelin expressing cancers using single photon emission computed tomography-computed tomography (SPECT-CT) imaging, PMID: 25756664
Phase II clinical trial of amatuximab, a chimeric antimesothelin antibody with pemetrexed and cisplatin in advanced unresectable pleural mesothelioma, PMID: 25231400
CA125 suppresses amatuximab immune-effector function and elevated serum levels are associated with reduced clinical response in first line mesothelioma patients, PMID: 29652548
Population pharmacokinetics and exposure-response relationship of amatuximab, an anti-mesothelin monoclonal antibody, in patients with malignant pleural mesothelioma and its application in dose selection, PMID: 26898299
Safety and biodistribution of 111In-amatuximab in patients with mesothelin expressing cancers using single photon emission computed tomography-computed tomography (SPECT-CT) imaging, PMID: 25756664
Phase II clinical trial of amatuximab, a chimeric antimesothelin antibody with pemetrexed and cisplatin in advanced unresectable pleural mesothelioma, PMID: 25231400
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
mesothelin isoform 1 preproprotein
NCBI Official Synonym Full Names
mesothelin
NCBI Official Symbol
MSLN
NCBI Official Synonym Symbols
MPF; SMRP
NCBI Protein Information
mesothelin; CAK1 antigen; megakaryocyte potentiating factor; soluble MPF mesothelin related protein; pre-pro-megakaryocyte-potentiating factor
UniProt Protein Name
Mesothelin
UniProt Gene Name
MSLN
UniProt Synonym Gene Names
MPF; MPF
UniProt Entry Name
MSLN_HUMAN
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Product Notes
The MSLN msln (Catalog #AAA120095) is an Antibody produced from Chimeric and is intended for research purposes only. The product is available for immediate purchase. The Research Grade Amatuximab reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "Amatuximab, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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