Mouse Anti Mullerian Hormone (AMH)/Mullerian Inhibiting Substance (MIS) Monoclonal Antibody | anti-AMH antibody
Anti Mullerian Hormone (AMH)/Mullerian Inhibiting Substance (MIS) Mouse Monoclonal Antibody [Clone AMH/300]
Reactivity
Human, Mouse, Sheep and Baboon
Applications
Immunohistochemistry, Western Blot
Synonyms
Anti Mullerian Hormone (AMH)/Mullerian Inhibiting Substance (MIS), Antibody; Anti Mullerian Hormone (AMH)/Mullerian Inhibiting Substance (MIS) Mouse Monoclonal Antibody [Clone AMH/300]; Muellerian inhibiting factor (MIF); anti-AMH antibody
Host
Mouse
Reactivity
Human, Mouse, Sheep and Baboon
Clonality
Monoclonal
Isotype
Mouse/IgG1, kappa
Clone Number
AMH/300
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0. 05% BSA & 0. 05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
Purified Ab with BSA and Azide at 200ug/ml
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
Applicable Applications for anti-AMH antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
Recombinant fragment of the C-terminus of human AMH (aa 460-560) (exact sequence is proprietary)
Cellular Localization
Secreted
Positive Control
Human or mouse ovary tissue.
Hu-chromosome Location
19p13.3
Unigene
112432
Preparation and Storage
Antibody with azide: store at 2 to 8 degree C
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Related Product Information for anti-AMH antibody
The transforming growth factor beta(TGFbeta) superfamily is composed of numerous growth and differentiation factors, including TGFbeta1-3, Mullerian inhibiting substance (MIS), growth/differentiation factor (GDF) 1-9, bone morphogenic protein (BMP) 2-8, glial cell line-derived neurotrophic factor (GDNF), Inhibin alpha,beta-A, beta-B and beta-C, Lefty and Nodal. Members of the TGFbetasuperfamily are involved in embryonic development and adult tissue homeostasis. The MIS glycoprotein is produced by the Sertoli cells of the testes. Fetal testes produce both MIS and testosterone, the presence of which result in male offspring. Absence of MIS and testosterone in a developing fetus results in the induction of Mullerian duct differentiation, and Wolffian duct development is not induced. Testosterone induces the differentiation of the Wolffian ducts whereas MIS causes regression of the Muellerian duct. MIS inhibits the growth of tumors derived from tissues of Mullerian duct origin. MIS can also inhibit the autophosphorylation of the EGF receptor in vitro. Defects in anti-Muellerian hormone are the cause of persistent Muellerian duct syndrome type I (PMDS-1). PMDS-1 is a form of male pseudo hermaphroditism characterized by a failure of Muellerian duct regression in otherwise normal males.
NCBI and Uniprot Product Information
NCBI GeneID
Molecular Weight
70kDa (reduced)
140kDa (nonreduced)
140kDa (nonreduced)
Similar Products
Product Notes
The AMH (Catalog #AAA215681) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti Mullerian Hormone (AMH)/Mullerian Inhibiting Substance (MIS) Mouse Monoclonal Antibody [Clone AMH/300] reacts with Human, Mouse, Sheep and Baboon and may cross-react with other species as described in the data sheet. AAA Biotech's Anti Mullerian Hormone (AMH)/Mullerian Inhibiting Substance (MIS) can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the AMH for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Anti Mullerian Hormone (AMH)/Mullerian Inhibiting Substance (MIS), Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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