Mouse anti-Human AP2 beta Monoclonal Antibody | anti-TFAP2B antibody

AP2 beta Antibody

Cat. Num. AAA312057

• Gene Names: TFAP2B; AP-2B; AP2-B; MGC21381
• Reactivity: Human
• Applications: Flow Cytometry, Functional Assay, Western Blot
• Purity: ProA affinity purified
• Synonyms: AP2 beta, Antibody; AP2 beta Antibody; Activating enhancer binding protein 2 beta antibody; Activating enhancer-binding protein 2-beta antibody; AP 2B antibody; AP2 B antibody; AP2-beta antibody; AP2B antibody; AP2B_HUMAN antibody; AP2beta antibody; MGC21381 antibody; OTTHUMP00000039925 antibody; PDA2 antibody; TFAP 2B antibody; Tfap2b antibody; Transcription factor AP 2 beta antibody; Transcription factor AP-2-beta antibody; Transcription factor AP2 beta antibody; anti-TFAP2B antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Clone Number: G1-F7
• Purity/Purification: ProA affinity purified
• Form/Format: 1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

• Applicable Applications for anti-TFAP2B antibody: FCM/FACS (Flow Cytometry), WB (Western Blot)
• Immunogen: Recombinant protein
• Conjugation: Unconjugated
• Preparation and Storage: Store at -20 degree C.

FCM/FACS (Flow Cytometry)

(Flow cytometric analysis of SK-N-SH cells with AP2 beta antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).)

WB (Western Blot)

(Western blot analysis of AP2 beta on SK-N-SH cell lysate using anti- AP2 beta antibody at 1/1, 000 dilution.)

WB (Western Blot)

(Western blot analysis of AP2 beta on HEK293 (1) and AP2 beta -hIgGFc transfected HEK293 (2) cell lysate using anti- AP2 beta antibody at 1/1, 000 dilution.)

WB (Western Blot)

(Western blot analysis of AP2 beta on human AP2 beta recombinant protein using anti- AP2 beta antibody at 1/1, 000 dilution.)

Related Product Information for anti-TFAP2B antibody

AP-2 transcription factor family members include AP-2alpha, AP-2beta and AP-2gamma, which specifically bind to the DNA consensus sequence CCCCAGGC and initiate transcription of selected genes. AP-2, also known as ERF-1, plays a role in regulating estrogen receptor expression. AP-2beta , a splice variant of AP-2alpha, inhibits AP-2 activity. Besides subscribing to the AP-2 complex, AP-2alpha, AP-2beta and AP-2gamma proteins compose the OB2-1 transcription factor complex. OB2-1 specifically upregulates expression of the proto-oncogene c-ErbB-2, which is overexpressed in 25-30% of breast cancers. AP-2alpha may play an important role in the development of ectodermal-derived tissues. Deleterious mutations involving the AP-2alpha gene are linked to microphthalmia, corneal clouding and other anterior eye chamber defects. The ubiquitously expressed AP-4 transcription factor specifically binds to the DNA consensus sequence 5'-CAGCTG-3'. AP-4 interacts with promoters for immunoglobulin-kappa gene families and simian virus 40. AP-4 may enhance the transcription of the human Huntington's disease gene. AP-4 is a helix-loop-helix protein that contains two distinctive leucine repeat elements.

Product Categories/Family for anti-TFAP2B antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 118582289
• NCBI GeneID: 7021
• NCBI Accession #: NP_003212.2
• NCBI GenBank Nucleotide #: NM_003221.3
• UniProt Accession #: Q92481; Q5JYX6; Q9NQ63; Q9NU99; Q9UJI7; Q9Y214; Q9Y3K3
• Molecular Weight: 50,474 Da
• NCBI Official Full Name: transcription factor AP-2-beta
• NCBI Official Synonym Full Names: transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
• NCBI Official Symbol: TFAP2B
• NCBI Official Synonym Symbols: AP-2B; AP2-B; MGC21381
• NCBI Protein Information: transcription factor AP-2-beta; AP2-beta; OTTHUMP00000016595; activating enhancer binding protein 2 beta; activating enhancer-binding protein 2-beta
• UniProt Protein Name: Transcription factor AP-2-beta
• UniProt Gene Name: TFAP2B
• UniProt Entry Name: AP2B_HUMAN