SDS-PAGE
(SDS PAGE for Apolizumab)
anti-Human Apolizumab Monoclonal Antibody | anti-HLA-DRB1 antibody
Research Grade Apolizumab
Gene Names
HLA-DRB1; SS1; DRB1; DRw10; HLA-DRB; HLA-DR1B
Reactivity
Human
Purity
>95% by SDS-PAGE; Purification: Protein A or G purified from cell culture supernatant.
Synonyms
Apolizumab, Antibody; Research Grade Apolizumab; Hu1D10; HLA class II histocompatibility antigen; DRB1 beta chain; Human leukocyte antigen DRB1; HLA-DRB1; anti-HLA-DRB1 antibody
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1-nd
Purity/Purification
>95% by SDS-PAGE; Purification: Protein A or G purified from cell culture supernatant.
Form/Format
Liquid. 0.01M PBS, pH7.4
Concentration
2.22 mg/ml (varies by lot)
Expression System
XtenCHO
Host Species
Humanized
CAS
267227-08-7
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at +4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
SDS-PAGE
(SDS PAGE for Apolizumab)
SDS-PAGE
(SDS PAGE for Apolizumab)
Product Categories/Family for anti-HLA-DRB1 antibody
References
A humanized HLA-DR antibody (hu1D10, apolizumab) in combination with granulocyte colony-stimulating factor (filgrastim) for the treatment of non-Hodgkin's lymphoma: a pilot study, PMID: 17071489
A phase I/II dose escalation study of apolizumab (Hu1D10) using a stepped-up dosing schedule in patients with chronic lymphocytic leukemia and acute leukemia, PMID: 19860603
Immunotherapy of non-Hodgkin's lymphoma with hLL2 (epratuzumab, an anti-CD22 monoclonal antibody) and Hu1D10 (apolizumab), PMID: 28140096
Novel therapies for chronic lymphocytic leukemia, PMID: 15010151
Targeting HLA-DR, PMID: 19886843
A phase I/II dose escalation study of apolizumab (Hu1D10) using a stepped-up dosing schedule in patients with chronic lymphocytic leukemia and acute leukemia, PMID: 19860603
Immunotherapy of non-Hodgkin's lymphoma with hLL2 (epratuzumab, an anti-CD22 monoclonal antibody) and Hu1D10 (apolizumab), PMID: 28140096
Novel therapies for chronic lymphocytic leukemia, PMID: 15010151
Targeting HLA-DR, PMID: 19886843
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
major histocompatibility complex, class II, DR beta 1
NCBI Official Synonym Full Names
major histocompatibility complex, class II, DR beta 1
NCBI Official Symbol
HLA-DRB1
NCBI Official Synonym Symbols
SS1; DRB1; DRw10; HLA-DRB; HLA-DR1B
NCBI Protein Information
major histocompatibility complex, class II, DR beta 1; DW2.2/DR2.2; MHC class II antigen; lymphocyte antigen DRB1; MHC class II HLA-DRw10-beta; human leucocyte antigen DRB1; MHC class II HLA-DR beta 1 chain; MHC class II HLA-DR-beta cell surface glycoprot
UniProt Protein Name
HLA class II histocompatibility antigen, DRB1-15 beta chain
UniProt Gene Name
HLA-DRB1
UniProt Synonym Gene Names
HLA-DRB2
UniProt Entry Name
2B1F_HUMAN
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Product Notes
The HLA-DRB1 hla-drb1 (Catalog #AAA119993) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Research Grade Apolizumab reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "Apolizumab, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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