IHC (Immunohiostchemistry)
Mouse anti-Human bcl-2 Monoclonal Antibody | anti-bcl-2 antibody
bcl-2
Gene Names
Bcl2; Bcl-2
Reactivity
Human
Synonyms
bcl-2, Antibody; bcl-2; anti-bcl-2 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1/K
Clone Number
BCL2/A4
Form/Format
Anti-bcl-2 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Control
Tonsil, Lymph Node
Localization
Cytoplasmic
Reactivity Note
Paraffin, Frozen
Preparation and Storage
Store at 2 to 8 degree C in the dark.
IHC (Immunohiostchemistry)
IHC (Immunohiostchemistry)
Dilution Info
Dilution Info
Related Product Information for anti-bcl-2 antibody
bcl-2 is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of bcl-2, such as in the case of translocation of bcl-2 to Ig heavy-chain loci, is thought to be the cause of Follicular Lymphoma. Anti-bcl-2 has shown consistent negative reaction on reactive germinal centers and positive staining of neoplastic follicles in Follicular Lymphoma. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. This antibody may also be used in distinguishing between those Follicular Lymphomas that express bcl-2 protein and the small number in which the neoplastic cells are bcl-2-negative. Anti-bcl-2 has been used as a predictive biomarker for recurrence of Cancer of the Breast and Non-Small-Cell Carcinoma of the Lung.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
26,622 Da
NCBI Official Full Name
BCL-2
NCBI Official Synonym Full Names
B-cell CLL/lymphoma 2
NCBI Official Symbol
Bcl2
NCBI Official Synonym Symbols
Bcl-2
NCBI Protein Information
apoptosis regulator Bcl-2; Bcl2-like protein; B-cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene
UniProt Protein Name
Apoptosis regulator Bcl-2
UniProt Gene Name
Bcl2
UniProt Synonym Gene Names
Bcl-2
UniProt Entry Name
BCL2_RAT
Similar Products
Product Notes
The bcl-2 bcl2 (Catalog #AAA59171) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The bcl-2 reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "bcl-2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.