Hamster Bcl-3 Monoclonal Antibody | anti-BCL3 antibody
Bcl-3 Monoclonal Antibody
Gene Names
BCL3; BCL4; D19S37
Applications
Immunoblot, Western Blot, ELISA
Synonyms
Bcl-3, Antibody; Bcl-3 Monoclonal Antibody; Bcl-3; anti-BCL3 antibody
Host
Hamster
Clonality
Monoclonal
Specificity
Bcl-3 [Human and mouse Bcl-3]
This antibody recognizes human and mouse Bcl-3.
This antibody recognizes human and mouse Bcl-3.
Form/Format
100 ug IgG in PBS, pH 7.4, purified by Protein G affinity chromatography.
Applicable Applications for anti-BCL3 antibody
IB (Immunoblot), ELISA
Immunogen
Recombinant mouse Bcl-3-6His.
Stabilizer
None
Preservatives
None. Available on request
Dilutions Instructions
Dilute in PBS or medium which is identical to that used in the assay system.
Preparation and Storage
This antibody is stable for at least one (1) year at -20 degree C. Avoid multiple freeze-thaw cycles.
Related Product Information for anti-BCL3 antibody
The gene encoding Bcl-3 was first identified as the gene altered in some cases of chronic B cell lymphocytic leukemia and was later found to belong to the I kappa B subfamily of inhibitors of NF kappa B transcription factors. Bcl-3 does not have DNA-binding activity, but it interacts with NF kappa B1 and NF kappa B2 which, when bound to DNA, repress gene transcription. Therefore, Bcl-3 may promote gene expression that is repressed by members of the NF kappa B family. Bcl-3 RNA is highly expressed in spleen and liver with lower levels of expression in heart, skeletal muscle, lung, kidney, and testes.
Product Categories/Family for anti-BCL3 antibody
References
Mitchell, TC et al. (2001) Nature Immunology 2: 397-402.
Watanabe, N et al. (1997) EMBO J 16: 3609-20.
Nolan, GP et al. (1993) Molecular and Cellular Biology 13: 3557-66.
Watanabe, N et al. (1997) EMBO J 16: 3609-20.
Nolan, GP et al. (1993) Molecular and Cellular Biology 13: 3557-66.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
47,584 Da
NCBI Official Full Name
B-cell lymphoma 3 protein
NCBI Official Synonym Full Names
B-cell CLL/lymphoma 3
NCBI Official Symbol
BCL3
NCBI Official Synonym Symbols
BCL4; D19S37
NCBI Protein Information
B-cell lymphoma 3 protein; BCL-3; OTTHUMP00000200151; OTTHUMP00000200152; proto-oncogene BCL3; B-cell leukemia/lymphoma 3; B-cell lymphoma 3-encoded protein; chronic lymphatic leukemia protein
UniProt Protein Name
B-cell lymphoma 3 protein
UniProt Gene Name
BCL3
UniProt Synonym Gene Names
BCL4; D19S37
UniProt Entry Name
BCL3_HUMAN
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Product Notes
The BCL3 bcl3 (Catalog #AAA47651) is an Antibody produced from Hamster and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Bcl-3 can be used in a range of immunoassay formats including, but not limited to, IB (Immunoblot), ELISA. Researchers should empirically determine the suitability of the BCL3 bcl3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Bcl-3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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