Application Data
(The purity of this product is >95% as determined by SEC-HPLC.)
Chimeric anti-Human Brentuximab Vedotin Monoclonal Antibody | anti-TNFRSF8 antibody
Research Grade Brentuximab
Gene Names
TNFRSF8; CD30; Ki-1; D1S166E
Reactivity
Human
Purity
>95%; Protein A or G purified from cell culture supernatant.
Synonyms
Brentuximab Vedotin, Antibody; Research Grade Brentuximab; SGN-35; cAC10-Val-Cit-MMAE; CD30L receptor; Ki-1 antigen; CD30; TNFRSF8; D1S166E; Tumor necrosis factor receptor superfamily member 8; Lymphocyte activation antigen CD30; anti-TNFRSF8 antibody
Host
Chimeric
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1-kappa
Purity/Purification
>95%; Protein A or G purified from cell culture supernatant.
Form/Format
Liquid. 100 mM Pro-Ac, 20 mM Arg, pH 5.0
Concentration
7.22 mg/ml (varies by lot)
Expression System
Mammalian Cells
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Store at -20 degree C short term.
Store at -80 degree C long term.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at -80 degree C long term.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Application Data
(The purity of this product is >95% as determined by SEC-HPLC.)
Application Data
(The purity of this product is >95% as determined by SEC-HPLC.)
SDS-PAGE
(SDS PAGE for Brentuximab Vedotin)
SDS-PAGE
(SDS PAGE for Brentuximab Vedotin)
Product Categories/Family for anti-TNFRSF8 antibody
References
Brentuximab Vedotin: A Review in CD30-Positive Hodgkin Lymphoma, PMID: 28190142
Brentuximab vedotin as consolidation therapy after autologous stem-cell transplantation in patients with Hodgkin's lymphoma at risk of relapse or progression (AETHERA): a randomised, double-blind, placebo-controlled, phase 3 trial, PMID: 25796459
Brentuximab vedotin with chemotherapy for stage III/IV classical Hodgkin lymphoma: 3-year update of the ECHELON-1 study, PMID: 31945149
Brentuximab vedotin in the treatment of CD30+ PTCL, PMID: 31697814
Brentuximab vedotin or physician's choice in CD30-positive cutaneous T-cell lymphoma (ALCANZA): an international, open-label, randomised, phase 3, multicentre trial, PMID: 28600132
Brentuximab vedotin as consolidation therapy after autologous stem-cell transplantation in patients with Hodgkin's lymphoma at risk of relapse or progression (AETHERA): a randomised, double-blind, placebo-controlled, phase 3 trial, PMID: 25796459
Brentuximab vedotin with chemotherapy for stage III/IV classical Hodgkin lymphoma: 3-year update of the ECHELON-1 study, PMID: 31945149
Brentuximab vedotin in the treatment of CD30+ PTCL, PMID: 31697814
Brentuximab vedotin or physician's choice in CD30-positive cutaneous T-cell lymphoma (ALCANZA): an international, open-label, randomised, phase 3, multicentre trial, PMID: 28600132
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
tumor necrosis factor receptor superfamily member 8 isoform 1
NCBI Official Synonym Full Names
tumor necrosis factor receptor superfamily member 8
NCBI Official Symbol
TNFRSF8
NCBI Official Synonym Symbols
CD30; Ki-1; D1S166E
NCBI Protein Information
tumor necrosis factor receptor superfamily member 8
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 8
UniProt Gene Name
TNFRSF8
UniProt Synonym Gene Names
CD30; D1S166E
UniProt Entry Name
TNR8_HUMAN
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Product Notes
The TNFRSF8 tnfrsf8 (Catalog #AAA120068) is an Antibody produced from Chimeric and is intended for research purposes only. The product is available for immediate purchase. The Research Grade Brentuximab reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "Brentuximab Vedotin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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