IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human hepatocellular carcinoma stained with C1QB Mouse Monoclonal Antibody (C1QB/2962).)
Mouse anti-Human C1QB/Complement C1q B-Chain Monoclonal Antibody | anti-C1QB antibody
C1QB/Complement C1q B-Chain Mouse Monoclonal Antibody [Clone C1QB/2962]
Reactivity
Human
Applications
Immunohistochemistry
Synonyms
C1QB/Complement C1q B-Chain, Antibody; C1QB/Complement C1q B-Chain Mouse Monoclonal Antibody [Clone C1QB/2962]; C1QB; Complement component 1 q subcomponent B chain; Complement component C1q B chain; anti-C1QB antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
Mouse/IgG, kappa
Clone Number
C1QB/2962
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0. 05% BSA & 0. 05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
Purified Ab with BSA and Azide at 200ug/ml
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
Applicable Applications for anti-C1QB antibody
IHC (Immunohistochemistry)
Immunogen
Recombinant fragment (around aa 41-188) of human C1QB protein (exact sequence is proprietary)
Cellular Localization
Cell surface, Cytoplasm
Positive Control
Human liver, kidney or brain tissue.
Hu-chromosome Location
1p36.12
Unigene
8986
Preparation and Storage
Antibody with azide: store at 2 to 8 degree C
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human hepatocellular carcinoma stained with C1QB Mouse Monoclonal Antibody (C1QB/2962).)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human hepatocellular carcinoma stained with C1QB Mouse Monoclonal Antibody (C1QB/2962).)
Related Product Information for anti-C1QB antibody
C1q, a subcomponent of the classical complement pathway, is composed of nine subunits that mediate classical complement activation and thereby play an important role in the immune response. Six of these subunits are disulfide-linked dimers of chains A and B, while three of these subunits, designated C1q-A through C1q-C, are disulfide-linked dimers of chain C. Each chain contains an N-terminal collagen-like region and a C-terminal C1q globular domain. The presence of receptors for C1q on effector cells modulates its activity, which may be antibody-dependent or independent. Macrophages are the primary source of C1q, while anti-inflammatory drugs as well as cytokines differentially regulate expression of the mRNA as well as the protein. C1q deficiency is associated with lupus erythematosus and glomerulonephritis.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
26,722 Da
NCBI Official Full Name
complement C1q subcomponent subunit B
NCBI Official Synonym Full Names
complement component 1, q subcomponent, B chain
NCBI Official Symbol
C1QB
NCBI Protein Information
complement C1q subcomponent subunit B; complement component C1q, B chain; complement subcomponent C1q chain B; complement component 1, q subcomponent, beta polypeptide
UniProt Protein Name
Complement C1q subcomponent subunit B
UniProt Gene Name
C1QB
UniProt Entry Name
C1QB_HUMAN
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Product Notes
The C1QB c1qb (Catalog #AAA215958) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The C1QB/Complement C1q B-Chain Mouse Monoclonal Antibody [Clone C1QB/2962] reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's C1QB/Complement C1q B-Chain can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the C1QB c1qb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "C1QB/Complement C1q B-Chain, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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