Mouse Calpain I (large subunit, p80) Monoclonal Antibody | anti-CAPN1 antibody
Calpain I (large subunit, p80)
Gene Names
CAPN1; CANP; muCL; CANP1; CANPL1; muCANP
Reactivity
Human, Mouse, Rat, Bovine
Applications
ELISA, Immunoprecipitation, Western Blot
Purity
Protein A/G Chromatography
Synonyms
Calpain I (large subunit, p80), Antibody; Calpain I (large subunit, p80); Mouse Anti-Calpain I; u-Calpain (Large subunit; p80); Monoclonal Antibody; anti-CAPN1 antibody
Host
Mouse
Reactivity
Human, Mouse, Rat, Bovine
Clonality
Monoclonal
Isotype
IgG1
Clone Number
15C10
Purity/Purification
Protein A/G Chromatography
Form/Format
Provided as a solution containing phosphate buffered saline, 0.08% sodium azide and 50% glycerol.
Sequence Length
714
Applicable Applications for anti-CAPN1 antibody
ELISA, IP (Immunoprecipitation), WB (Western Blot)
Source
Hybridoma produced by the fusion of splenocytes from mice immunized with human calpain I purified from placenta with mouse myeloma.
Conjugation
Unconjugated
Preparation and Storage
Product should be stored at -20 degree C. Aliquot to avoid freeze/thaw cycles
Related Product Information for anti-CAPN1 antibody
The calpains are calcium-dependent cysteine proteases that are widely expressed in mammalian systems. Both m-calpain (calpain II) and -calpain (calpain I) are composed of an 80 kD subunit and a 30 kD subunit. Whereas the 30 kD subunit is shared by both enzymes, the larger catalytic subunits are different and exhibit the distinct Ca ++ requirements that are suggested by their names. Whereas m-calpain requires millimolar (mM) levels of calcium, -calpain is active at micromolar (uM) concentrations of Ca ++. In addition to the ubiquitously expressed m- and calpains, some tissue-specific calpains have been identified. The calpains appear to serve multiple physiological roles, and ideas concerning the functions of these enzymes are in a state of rapid flux.
Product Categories/Family for anti-CAPN1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
calpain-1 catalytic subunit
NCBI Official Synonym Full Names
calpain 1, (mu/I) large subunit
NCBI Official Symbol
CAPN1
NCBI Official Synonym Symbols
CANP; muCL; CANP1; CANPL1; muCANP
NCBI Protein Information
calpain-1 catalytic subunit; CANP 1; calpain mu-type; micromolar-calpain; calpain-1 large subunit; calpain, large polypeptide L1; calcium-activated neutral proteinase 1; cell proliferation-inducing protein 30; cell proliferation-inducing gene 30 protein
UniProt Protein Name
Calpain-1 catalytic subunit
UniProt Gene Name
CAPN1
UniProt Synonym Gene Names
CANPL1; CANP 1; muCANP
UniProt Entry Name
CAN1_HUMAN
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Product Notes
The CAPN1 capn1 (Catalog #AAA60490) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Calpain I (large subunit, p80) reacts with Human, Mouse, Rat, Bovine and may cross-react with other species as described in the data sheet. AAA Biotech's Calpain I (large subunit, p80) can be used in a range of immunoassay formats including, but not limited to, ELISA, IP (Immunoprecipitation), WB (Western Blot). Researchers should empirically determine the suitability of the CAPN1 capn1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Calpain I (large subunit, p80), Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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