Rabbit cAMP Protein Kinase Catalytic Subunit Monoclonal Antibody | anti-cAMP antibody

Recombinant cAMP Protein Kinase Catalytic Subunit Monoclonal Antibody

Cat. Num. AAA178836

• Gene Names: PRKACA; PKACA
• Reactivity: Human, Mouse, Rat
• Applications: Immunoprecipitation, Immunofluorescence, Immunohistochemistry, Western Blot
• Purity: Affinity Purified
• Synonyms: cAMP Protein Kinase Catalytic Subunit, Antibody; Recombinant cAMP Protein Kinase Catalytic Subunit Monoclonal Antibody; cAMP dependent protein kinase alpha catalytic subunit; cAMP dependent protein kinase beta catalytic subunit; cAMP dependent protein kinase catalytic beta subunit isoform 4ab; cAMP dependent protein kinase catalytic subunit alpha; isoform 1; cAMP dependent protein kinase catalytic subunit beta; cAMP-dependent protein kinase catalytic subunit alpha; KAPCA; PKA C alpha; PKA C beta; PKA C-alpha; PKACA; PKACB; PPNAD4; PRKACA; PRKACAA; PRKACB; Protein kinase A catalytic subunit alpha; Protein kinase A catalytic subunit; Protein kinase A catalytic subunit beta; Protein kinase cAMP dependent catalytic alpha; Protein kinase cAMP dependent catalytic beta; anti-cAMP antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Monoclonal
• Isotype: IgG
• Clone Number: R07-8H3
• Purity/Purification: Affinity Purified
• Form/Format: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
• Concentration: 300ug/mL (varies by lot)

• Applicable Applications for anti-cAMP antibody: IP (Immunoprecipitation), IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
• Immunogen: A synthetic peptide of human cAMP Protein Kinase Catalytic subunit
• Research Area: Cancer, Metabolism, Signal Transduction
• Preparation and Storage: Storage: -20 degree C/One year. Avoid freeze/thaw cycles.

IF (Immunofluorescence)

(Immunofluorescence of cAMP Protein Kinase Catalytic subunit (green) in Hela cells using cAMP Protein Kinase Catalytic subunit Rabbit mAb at dilution 1:50, and DAPI(blue))

IHC (Immunohiostchemistry)

(Immunohistochemistry of cAMP Protein Kinase Catalytic subunit in paraffin-embedded Human colon cancer tissue using cAMP Protein Kinase Catalytic subunit Rabbit mAb at dilution 1:100)

WB (Western Blot)

(Western blot detection of cAMP Protein Kinase Catalytic subunit in K562,C6,3T3,Hela cell lysates using cAMP Protein Kinase Catalytic subunit Rabbit mAb(1:1000 diluted).Predicted band size:41kDa.Observed band size:41kDa.)

Related Product Information for anti-cAMP antibody

This gene encodes one of the catalytic subunits of protein kinase A, which exists as a tetrameric holoenzyme with two regulatory subunits and two catalytic subunits, in its inactive form. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. cAMP-dependent phosphorylation of proteins by protein kinase A is important to many cellular processes, including differentiation, proliferation, and apoptosis. Constitutive activation of this gene caused either by somatic mutations, or genomic duplications of regions that include this gene, have been associated with hyperplasias and adenomas of the adrenal cortex and are linked to corticotropin-independent Cushing's syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. Tissue-specific isoforms that differ at the N-terminus have been described, and these isoforms may differ in the post-translational modifications that occur at the N-terminus of some isoforms.

Product Categories/Family for anti-cAMP antibody

Antibodies; Primary Antibodies; Recombinant Antibody

NCBI and Uniprot Product Information

• NCBI GI #: 4506055
• NCBI GeneID: 5566
• NCBI Accession #: NP_002721.1
• NCBI GenBank Nucleotide #: NM_002730.3
• UniProt Accession #: P17612; Q32P54; Q9H2Y0; Q9NRB4; Q9NRH9
• Molecular Weight: 351
• NCBI Official Full Name: cAMP-dependent protein kinase catalytic subunit alpha isoform 1
• NCBI Official Synonym Full Names: protein kinase, cAMP-dependent, catalytic, alpha
• NCBI Official Symbol: PRKACA
• NCBI Official Synonym Symbols: PKACA
• NCBI Protein Information: cAMP-dependent protein kinase catalytic subunit alpha; PKA C-alpha; protein kinase A catalytic subunit; cAMP-dependent protein kinase catalytic subunit alpha, isoform 1
• UniProt Protein Name: cAMP-dependent protein kinase catalytic subunit alpha
• UniProt Gene Name: PRKACA
• UniProt Synonym Gene Names: PKACA; PKA C-alpha
• UniProt Entry Name: KAPCA_HUMAN