IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human liver carcinoma in colon stained with Cathepsin D Mouse Monoclonal Antibody (CTSD/4497).)
Mouse anti-Human Cathepsin D Monoclonal Antibody | anti-CTSD antibody
Cathepsin D (Tumor Marker) Mouse Monoclonal Antibody [Clone CTSD/4497]
Gene Names
CTSD; CPSD; CLN10
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Synonyms
Cathepsin D, Antibody; Cathepsin D (Tumor Marker) Mouse Monoclonal Antibody [Clone CTSD/4497]; Cathepsin D (Tumor Marker); CatD; Cathepsin D; Ceroid lipofuscinosis neuronal 10; CLN10; CPSD; Epididymis secretory sperm binding protein Li 130P; Lysosomal aspartyl peptidase; Lysosomal aspartyl protease; anti-CTSD antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
Mouse/IgG1, kappa
Clone Number
CTSD/4497
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0. 05% BSA & 0. 05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
Purified Ab with BSA and Azide at 200ug/ml
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
Applicable Applications for anti-CTSD antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
Purified His-tagged CTSD protein
Cellular Localization
Cytoplasm
Positive Control
MCF-7, A431 or SK-BR3 cells. Kidney, liver, lung or breast.
Hu-chromosome Location
11p15.5
Unigene
654447
Preparation and Storage
Antibody with azide: store at 2 to 8 degree C
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human liver carcinoma in colon stained with Cathepsin D Mouse Monoclonal Antibody (CTSD/4497).)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human liver carcinoma in colon stained with Cathepsin D Mouse Monoclonal Antibody (CTSD/4497).)
Related Product Information for anti-CTSD antibody
Cathepsin D is a ubiquitously expressed lysosomal aspartyl protease involved in the normal degradation of proteins. It is synthesized as an inactive 43kDa preprocathepsin D that is cleaved and glycosylated to form a 46kDa procathepsin D and then further cleaved to produce 28kDa and 15kDa subunits (heavy and light chains, respectively). Cathepsin D exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
44,552 Da
NCBI Official Full Name
cathepsin D preproprotein
NCBI Official Synonym Full Names
cathepsin D
NCBI Official Symbol
CTSD
NCBI Official Synonym Symbols
CPSD; CLN10
NCBI Protein Information
cathepsin D; lysosomal aspartyl protease; lysosomal aspartyl peptidase; ceroid-lipofuscinosis, neuronal 10
UniProt Protein Name
Cathepsin D
UniProt Gene Name
CTSD
UniProt Synonym Gene Names
CPSD
UniProt Entry Name
CATD_HUMAN
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Product Notes
The CTSD ctsd (Catalog #AAA215584) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Cathepsin D (Tumor Marker) Mouse Monoclonal Antibody [Clone CTSD/4497] reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Cathepsin D can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the CTSD ctsd for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cathepsin D, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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