Application Data
((H) The arthritis severity was evaluated by the arthritis scores. (I) Paw swelling was measured every 5 days after anti-CD109 addition. (J) Paw photographs from mice with CIA captured on day 21 after starting anti-CD109 treatment.)
Mouse CD109 Monoclonal Antibody | anti-CD109 antibody
CD109 Neutralizing monoclonal antibody
Reactivity
Human, Mouse, Rat
Synonyms
CD109, Antibody; CD109 Neutralizing monoclonal antibody; 150 kDa TGF-beta-1-binding protein; activated T-cell marker CD109; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7; CD109; CD109 antigen; Gov platelet alloantigens; p180; Platelet-specific Gov antigen; r150; RP11-525G3.1; CPAMD7; anti-CD109 antibody
Host
Mouse
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Specificity
Antibody detects endogenous levels of total CD109.
Preparation and Storage
Store at -20C. Stable for 12 months from date of receipt.
Application Data
((H) The arthritis severity was evaluated by the arthritis scores. (I) Paw swelling was measured every 5 days after anti-CD109 addition. (J) Paw photographs from mice with CIA captured on day 21 after starting anti-CD109 treatment.)
Application Data
((H) The arthritis severity was evaluated by the arthritis scores. (I) Paw swelling was measured every 5 days after anti-CD109 addition. (J) Paw photographs from mice with CIA captured on day 21 after starting anti-CD109 treatment.)
Application Data
(Aneutralizing antibody against CD109 (anti-CD109) were designed for functional or treatment studies in RA FLSs and CIA.The migration (K) and invasion (L) of RA FLSs from six different patients (three males and three females) were assessed and quantified (graph below) after the addition of anti-CD109 (10 ug/mL) or IgG (10 ug/mL) and incubation for 24 hours. ***p)
Application Data
(Aneutralizing antibody against CD109 (anti-CD109) were designed for functional or treatment studies in RA FLSs and CIA.The migration (K) and invasion (L) of RA FLSs from six different patients (three males and three females) were assessed and quantified (graph below) after the addition of anti-CD109 (10 ug/mL) or IgG (10 ug/mL) and incubation for 24 hours. ***p)
Related Product Information for anti-CD109 antibody
CD109 is a member of the alpha2-macroglobulin/complement superfamily. The encoded GPI-linked glycoprotein is found on the cell surface of platelets, activated T-cells, and endothelial cells. The protein binds to and negatively regulates signaling of transforming growth factor beta (TGF-beta).
References
Guanhua Song. ect. CD109 regulates the inflammatory response and is required for the pathogenesis of rheumatoid arthritis. Ann Rheum Dis. 2019 Dec;78(12):1632-1641. doi: 10.1136/annrheumdis-2019-215473. Epub 2019 Aug 27.
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Product Notes
The CD109 (Catalog #AAA62493) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CD109 Neutralizing monoclonal antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "CD109, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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