IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human tonsil stained with CD138Recombinant Rabbit Monoclonal Antibody (SDC1/4378R).)
Rabbit anti-Human CD138/Syndecan-1 (SDC1) Monoclonal Antibody | anti-SDC1 antibody
CD138/Syndecan-1 (SDC1) (Plasma Cell Marker) Recombinant Rabbit Monoclonal Antibody [Clone SDC1/4378R]
Gene Names
SDC1; SDC; CD138; SYND1; syndecan
Reactivity
Human
Applications
Immunohistochemistry
Synonyms
CD138/Syndecan-1 (SDC1), Antibody; CD138/Syndecan-1 (SDC1) (Plasma Cell Marker) Recombinant Rabbit Monoclonal Antibody [Clone SDC1/4378R]; CD138/Syndecan-1 (SDC1) (Plasma Cell Marker); Heparan Sulfate Proteoglycan Fibroblast Growth Factor Receptor; SDC1; SYND1; Syndecan Proteoglycan 1; Syndecan-1; anti-SDC1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
Rabbit/IgG, kappa
Clone Number
SDC1/4378R
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0. 05% BSA & 0. 05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
Purified Ab with BSA and Azide at 200ug/ml
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
Applicable Applications for anti-SDC1 antibody
IHC (Immunohistochemistry)
Antibody Type
Recombinant Antibody
Immunogen
Recombinant fragment (around aa200-300) of human CD138 protein (exact sequence is proprietary)
Cellular Localization
Cell Surface
Positive Control
Human tonsil or lymph node.
Hu-chromosome Location
2p24.1
Unigene
224607
Preparation and Storage
Antibody with azide: store at 2 to 8 degree C
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human tonsil stained with CD138Recombinant Rabbit Monoclonal Antibody (SDC1/4378R).)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human tonsil stained with CD138Recombinant Rabbit Monoclonal Antibody (SDC1/4378R).)
Related Product Information for anti-SDC1 antibody
CD138, also designated syndecan-1, is a member of the syndecan family of four transmembrane spanning proteins capable of binding to heparan sulfate and chondroitin sulfate molecules. The syndecans main functions are to control cell growth and differentiation as well as to maintain cell adhesion and cell migration. Under normal conditions CD138 ispredominantly expressed on mature plasma cells and early preB-cells, while other haematolymphoid cells are negative. Various types of epithelial cells are also CD138 positive. Squamous epithelial cells show strong membranous and some cytoplasmic staining, except for the mature superficial squamous epithelial cells which are unstained. Mature mesenchymal and neural tissues are not stained. Among haematolymphoid neoplasms, CD138 is expressed in practically all cases of plasma cell malignancies. Among non-haematolymphoid neoplasms the expression of CD138 is found in various types of carcinoma. In the following, the large majority of cases is CD138 positive: skin squamous cell carcinoma and basal cell carcinoma, colorectal adenocarcinoma, cholangiocarcinoma, transitional cell carcinoma, endometrial adenocarcinoma, ductal and lobular breast carcinoma, hepatocellular carcinoma, renal cell carcinoma, and lung adenocarcinoma. CD138 is a very sensitive and specific marker for identification of plasma cells and plasma cell differentiation within haematolymphoid tissues in benign and neoplastic conditions.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
32,462 Da
NCBI Official Full Name
syndecan-1
NCBI Official Synonym Full Names
syndecan 1
NCBI Official Symbol
SDC1
NCBI Official Synonym Symbols
SDC; CD138; SYND1; syndecan
NCBI Protein Information
syndecan-1; CD138 antigen; syndecan proteoglycan 1; heparan sulfate proteoglycan fibroblast growth factor receptor
UniProt Protein Name
Syndecan-1
UniProt Gene Name
SDC1
UniProt Synonym Gene Names
SDC; SYND1
UniProt Entry Name
SDC1_HUMAN
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Product Notes
The SDC1 sdc1 (Catalog #AAA215909) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CD138/Syndecan-1 (SDC1) (Plasma Cell Marker) Recombinant Rabbit Monoclonal Antibody [Clone SDC1/4378R] reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD138/Syndecan-1 (SDC1) can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the SDC1 sdc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD138/Syndecan-1 (SDC1), Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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