IHC (Immunohiostchemistry)
(CD14 Antibody-Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE))
Mouse anti-Human CD14 Monoclonal Antibody | anti-CD14 antibody
CD14 Mouse anti-Human Monoclonal (7) Antibody
Reactivity
Human
Applications
Immunohistochemistry, Immunohistochemistry
Purity
Tissue culture supernatant
Synonyms
CD14, Antibody; CD14 Mouse anti-Human Monoclonal (7) Antibody; PathPlus CD14 Antibody (clone 7); CD14; CD14 molecule; CD14 antigen; anti-CD14 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
7
Specificity
Human CD14
Purity/Purification
Tissue culture supernatant
Form/Format
Filter sterilized and diluted in buffer, pH7.5, BSA, Sodium Azide
Applicable Applications for anti-CD14 antibody
IHC (Immunohistochemistry), IHC (Immunohistochemistry)
Target
Human CD14
Immunogen
Recombinant protein encoded the extracellular domain of human CD14
Conjugation
Unconjugated
Preparation and Storage
Store at 2-8 degree C. Avoid freeze/thaw cycles.
IHC (Immunohiostchemistry)
(CD14 Antibody-Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohiostchemistry)
(CD14 Antibody-Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohistochemistry)
(CD14 Antibody-Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohistochemistry)
(CD14 Antibody-Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE))
Related Product Information for anti-CD14 antibody
CD14 antibody is an unconjugated mouse monoclonal antibody to human CD14. Validated for IHC.
CD14, also called monocyte differentiation antigen CD14, is a co-receptor protein for bacterial lipopolysaccharide. It is a component of the innate immune system, enhancing responses to infection by sensitizing host cells to bacterial lipopolysaccharide and other microbial products. Binding to LPS activates the release of cytokines. CD14 has a membrane-bound form and a soluble form. It is expressed on macrophages, monocytes (specific marker for monocytic differentiation), neutrophils, dendritic cells, and enterocytes; the soluble form is secreted by the liver and by monocytes. Staining is used to identify monocytes and macrophages in normal tissues and leukemias (eg, acute monoblastic, acute myelomonocytic).
CD14, also called monocyte differentiation antigen CD14, is a co-receptor protein for bacterial lipopolysaccharide. It is a component of the innate immune system, enhancing responses to infection by sensitizing host cells to bacterial lipopolysaccharide and other microbial products. Binding to LPS activates the release of cytokines. CD14 has a membrane-bound form and a soluble form. It is expressed on macrophages, monocytes (specific marker for monocytic differentiation), neutrophils, dendritic cells, and enterocytes; the soluble form is secreted by the liver and by monocytes. Staining is used to identify monocytes and macrophages in normal tissues and leukemias (eg, acute monoblastic, acute myelomonocytic).
References
Science. 1990;249(4975):1431-1433. PMID: 1698311; Immunity. 1994;1(6):509-516. PMID: 7534618; J Hepatol. 1999;31(3):435-442. PMID: 10488701; Infect Immun. 1998;66(3):1135-1141. PMID: 9488406; Am J Clin Pathol. 2011;135(5):720-730. doi: 10.1309/AJCPZ46PMMAWJROT; -Leukemia. 2006;20(7):1321-1324. doi: 10.1038/sj.leu.2404242
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
53kDa
NCBI Official Full Name
monocyte differentiation antigen CD14
NCBI Official Synonym Full Names
CD14 molecule
NCBI Official Symbol
CD14
NCBI Protein Information
monocyte differentiation antigen CD14; myeloid cell-specific leucine-rich glycoprotein
UniProt Protein Name
Monocyte differentiation antigen CD14
UniProt Gene Name
CD14
UniProt Entry Name
CD14_HUMAN
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Product Notes
The CD14 cd14 (Catalog #AAA163089) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CD14 Mouse anti-Human Monoclonal (7) Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD14 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the CD14 cd14 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD14, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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