Rat anti-Mouse CD157 Monoclonal Antibody | anti-CD157 antibody
Anti-Mouse CD157, Purified (Clone KT157) (Rat IgG2c)
Reactivity
Mouse
Applications
Flow Cytometry, Functional Assay
Purity
Purified from ascitic fluid via Protein G Chromatography
Synonyms
CD157, Antibody; Anti-Mouse CD157, Purified (Clone KT157) (Rat IgG2c); CD157, Purified (Clone KT157) (Rat IgG2c); Purified Anti-Mouse CD157 Receptor Monoclonal Antibody; anti-CD157 antibody
Host
Rat
Reactivity
Mouse
Clonality
Monoclonal
Isotype
Rat IgG2c (Rat IgG 2b)
Clone Number
KT157
Specificity
CD157 (Mouse CD157)
Purity/Purification
Purified from ascitic fluid via Protein G Chromatography
Form/Format
Purified IgG buffered in PBS and 0.02% NaN3
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
298
Applicable Applications for anti-CD157 antibody
FCM/FACS (Flow Cytometry)
Hybridoma Production
Immunogen:T cell hybridoma J774
Donor: Mouse spleen cells
Fusion Partner: NSO Myeloma Partner
Donor: Mouse spleen cells
Fusion Partner: NSO Myeloma Partner
Isotype Control
CLCR2C00
Note
For maximum recovery of contents, spin down tube before use.
Preparation and Storage
For all formats, store at 4°C. For long term storage (Ascites, Purified, Biotin, FITC), aliquot and freeze unused portion at -20°C in volumes appropriate for single usage. Avoid freeze/thaw cycles.
Related Product Information for anti-CD157 antibody
anti-mouse CD157 monoclonal antibody detects the mouse CD157 receptor. CD157 also known as BP-3 Alloantigen or Bone marrow STromal cell antigen-1 (BST-1), is a 38-48 KDa differentially glycosylated glycosylphosphatidylinositol (GPI) anchored cell surface glycoprotein. CD157, like CD38 belongs to a family of genetically related pleiotropic ectoenzymes. The CD157 antigen is expressed on thymocytes, bone marrow B cells, neutrophils, macrophages, stromal cells, intestinal epithelial cells, the collecting tubules of the kidney and reticular cells in lymph nodes. The CD157 receptor has ADP ribosyl cyclase and cyclic ADP ribose hydrolase biochemical activities. Studies show CD157 is a receptor that induces reorganization of the cytoskeleton and significant changes in cell shape. CD157 is also a mediator of neutrophil adhesion and migration. Signals mediated by CD157 act through modulation of cytosolic [Ca2+]. CD157 is also involved in cellular adhesion to the extracellular matrix. This anti-body has been reported to work in Flow Cytometry.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
CD157 protein
NCBI Official Symbol
cd157
NCBI Protein Information
CD157 protein
Similar Products
Product Notes
The CD157 (Catalog #AAA74137) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The Anti-Mouse CD157, Purified (Clone KT157) (Rat IgG2c) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CD157 can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the CD157 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD157, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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