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product-image-AAA78232_FCM10.jpg FCM/FACS (Flow Cytometry) (Cell Surface flow analysis of hCD161 in PBMC (Lymphocytes) using 0.2ug/10^6 cells of CD161 clone (ABM2D74). Green represents isotype control; red represents anti-hCD161 antibody. Goat anti-mouse PE conjugated secondary antibody was used.)

Mouse anti-Human CD161 Monoclonal Antibody | anti-CD161 antibody

CD161 Monoclonal Antibody

Gene Names
KLRB1; NKR; CD161; CLEC5B; NKR-P1; NKRP1A; NKR-P1A; hNKR-P1A
Reactivity
Human
Applications
Flow Cytometry, Functional Assay, Immunohistochemistry, Western Blot
Purity
Protein G chromatography
Synonyms
CD161, Antibody; CD161 Monoclonal Antibody; anti-CD161 antibody
Ordering
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
Mouse IgG1, Kappa
Clone Number
ABM2D74
Purity/Purification
Protein G chromatography
Form/Format
Purified (Liquid)
Applicable Applications for anti-CD161 antibody
FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A full length of human CD161 protein were used as the immunogen for this antibody.
Content
25 ug in 50 ul/100 ug in 200 ul PBS containing 0.05% BSA and 0.05% and 0.05% sodium azide. Sodium azide is highly toxic.
Preparation and Storage
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C.
Avoid repeated freeze thaw cycles.

FCM/FACS (Flow Cytometry)

(Cell Surface flow analysis of hCD161 in PBMC (Lymphocytes) using 0.2ug/10^6 cells of CD161 clone (ABM2D74). Green represents isotype control; red represents anti-hCD161 antibody. Goat anti-mouse PE conjugated secondary antibody was used.)

product-image-AAA78232_FCM10.jpg FCM/FACS (Flow Cytometry) (Cell Surface flow analysis of hCD161 in PBMC (Lymphocytes) using 0.2ug/10^6 cells of CD161 clone (ABM2D74). Green represents isotype control; red represents anti-hCD161 antibody. Goat anti-mouse PE conjugated secondary antibody was used.)

IHC (Immunohistochemisry)

(Immunohistochemical analysis of CD161  in Transitional cell carcinoma of urinary bladder using CD161 antibody (Clone: ABM2D74) at 5 ug/ml.)

product-image-AAA78232_IHC11.jpg IHC (Immunohistochemisry) (Immunohistochemical analysis of CD161  in Transitional cell carcinoma of urinary bladder using CD161 antibody (Clone: ABM2D74) at 5 ug/ml.)

IHC (Immunohiostchemistry)

(Immunohistochemical analysis of CD161  in small cell carcinoma of esophagus using CD161 antibody (Clone: ABM2D74) at 5 ug/ml.)

product-image-AAA78232_IHC13.jpg IHC (Immunohiostchemistry) (Immunohistochemical analysis of CD161  in small cell carcinoma of esophagus using CD161 antibody (Clone: ABM2D74) at 5 ug/ml.)

WB (Western Blot)

(Expression analysis of CD161. Anti-CD161 antibody (Clone: ABM2D74) was tested at 2 ug/ml on Jurkat lysate.)

product-image-AAA78232_WB15.jpg WB (Western Blot) (Expression analysis of CD161. Anti-CD161 antibody (Clone: ABM2D74) was tested at 2 ug/ml on Jurkat lysate.)
Related Product Information for anti-CD161 antibody
CD161 is the human equivalent of mouse NK cell receptor P1A. It is a type II transmembrane glycoprotein with characteristics of the C-type lectin super family. The expression confines to lymphocytes found in human gut and liver, as well as blood, especially NK (natural killer) cells, Th17 (T helper 17) cells, and a population of unconventional T cells known as MAIT (mucosal-associated invariant T) cells. CD161 promotes T cell expansion and eventually has been identified as a marker of human IL-17-producing T cells. It plays a pivotal role in trans-endothelial migration and is also implicated in the pathogenesis of RA (rheumatoid arthritis) as well as graft-versus-host disease (GVHD).
Product Categories/Family for anti-CD161 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
killer cell lectin-like receptor subfamily B member 1
NCBI Official Synonym Full Names
killer cell lectin-like receptor subfamily B, member 1
NCBI Official Symbol
KLRB1
NCBI Official Synonym Symbols
NKR; CD161; CLEC5B; NKR-P1; NKRP1A; NKR-P1A; hNKR-P1A
NCBI Protein Information
killer cell lectin-like receptor subfamily B member 1
UniProt Protein Name
Killer cell lectin-like receptor subfamily B member 1
UniProt Gene Name
KLRB1
UniProt Synonym Gene Names
CLEC5B; NKRP1A; NKR-P1A
UniProt Entry Name
KLRB1_HUMAN

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Product Notes

The CD161 klrb1 (Catalog #AAA78232) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CD161 Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD161 can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the CD161 klrb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD161, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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