IHC (Immunohistochemistry)
(Immunohistochemistry: Human Tonsil (FFPE) stained with Mouse anti-CD196 (Cat# AAA71367 ) at 1:200 for 10 min @ RT. Staining of formalin-fixed tissue requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.)
Human anti-Human CD196 Monoclonal Antibody | anti-CD196 antibody
Mouse anti CD196 Monoclonal Antibody
Reactivity
Human
Applications
Flow Cytometry, Functional Assay, Immunohistochemistry
Purity
Purification: The mouse IgG is purified by Protein A-Affinity Chromatography according to Isotyping
Synonyms
CD196, Antibody; Mouse anti CD196 Monoclonal Antibody; CCR6; BN-1; DCR2; DRY6; CCR-6; CD196; CKRL3; GPR29; CKR-L3; CMKBR6; GPRCY4; STRL22; CC-CKR-6; C-C CKR-6; anti-CD196 antibody
Host
Human
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG
Clone Number
ZY912
Specificity
This antibody recognizes human CD196 (CCR6) protein. The other species are not tested.
Purity/Purification
Purification: The mouse IgG is purified by Protein A-Affinity Chromatography according to Isotyping
Form/Format
This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer
Applicable Applications for anti-CD196 antibody
FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry)
Positive Control
Kidney Tissue
Cellular Location
Cell Membrane
Preparation and Storage
The antibodies are stable for 12 months from date of receipt when stored at –20°C to –70°C. The antibodies can be stored at 2°C-8°C for three months without detectable loss of activity. Avoid repeated freezing-thawing cycles.
IHC (Immunohistochemistry)
(Immunohistochemistry: Human Tonsil (FFPE) stained with Mouse anti-CD196 (Cat# AAA71367 ) at 1:200 for 10 min @ RT. Staining of formalin-fixed tissue requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.)
IHC (Immunohistochemistry)
(Immunohistochemistry: Human Tonsil (FFPE) stained with Mouse anti-CD196 (Cat# AAA71367 ) at 1:200 for 10 min @ RT. Staining of formalin-fixed tissue requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.)
Related Product Information for anti-CD196 antibody
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. CCR6 has also recently been designated CD196 The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. It was shown that CC-chemokine cysteine motif chemokine ligand 20 (CCL20) and its physiological sole receptor CCR6 play a role in the onset, development and metastatic spread of various gastrointestinal cancer entities.
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Product Notes
The CD196 (Catalog #AAA71367) is an Antibody produced from Human and is intended for research purposes only. The product is available for immediate purchase. The Mouse anti CD196 Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD196 can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the CD196 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD196, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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