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Application Data
(Staining of CD223 transfected cells with Rat anti Mouse CD223:RPE)
Rat CD223 Monoclonal Antibody | anti-CD223 antibody
RAT ANTI MOUSE CD223
Gene Names
Lag3; Ly66; CD223; LAG-3
Applications
Flow Cytometry, Functional Assay
Synonyms
CD223, Antibody; RAT ANTI MOUSE CD223; anti-CD223 antibody
Host
Rat
Clonality
Monoclonal
Isotype
IgG1
Clone Number
C9B7W
Form/Format
Purified
Purified IgG - liquid
Purified IgG - liquid
Concentration
IgG concentration 1.0 mg/ml (varies by lot)
Sequence Length
521
Applicable Applications for anti-CD223 antibody
FCM/FACS (Flow Cytometry)
Perservative Stabilisers
0.09% Sodium Azide
Preparation
Preparation
Immunogen
Murine CD223 Ig fusion protein
Fusion Partners
Fusion Partners
Target Species
Mouse
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Shelf Life: 18 months from date of despatch.
Application Data
(Staining of CD223 transfected cells with Rat anti Mouse CD223:RPE)
Application Data
(Staining of CD223 transfected cells with Rat anti Mouse CD223:RPE)
Application Data
(Staining of CD223 transfected cells with Rat anti Mouse CD223)
Application Data
(Staining of CD223 transfected cells with Rat anti Mouse CD223)
Application Data
(Staining of CD223 transfected cells with Rat anti Mouse CD223:Alexa Fluor 488)
Application Data
(Staining of CD223 transfected cells with Rat anti Mouse CD223:Alexa Fluor 488)
Application Data
(Staining of CD223 transfected cells with Rat anti Mouse CD223:Alexa Fluor 647)
Application Data
(Staining of CD223 transfected cells with Rat anti Mouse CD223:Alexa Fluor 647)
Application Data
(Staining of CD223 transfected cells with Rat anti Mouse CD223)
Application Data
(Staining of CD223 transfected cells with Rat anti Mouse CD223)
Related Product Information for anti-CD223 antibody
Rat anti Mouse CD223 antibody, clone C9B7W recognizes murine lymphocyte activation gene-3 (LAG-3), a 70kD activation-induced cell surface molecule that is also referred to as CD223. Murine CD223 is expressed on activated CD4 positive and CD8 positive alpha/beta T lymphocytes and a subset of natural killer (NK) cells. CD223 binds to MHC class II molecules with high affinity and is reported to negatively regulate T cell homeostasis and T cell expansion. Clone C9B7W recognizes an epitope within the D2 domain of CD223. The antibody is reported to block the in vitro function of murine LAG-3 but studies suggest that the antibody does not block binding of LAG-3 to MHC class II (Workman et al. 2002).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
56,978 Da
NCBI Official Full Name
lymphocyte activation gene 3 protein
NCBI Official Synonym Full Names
lymphocyte-activation gene 3
NCBI Official Symbol
Lag3
NCBI Official Synonym Symbols
Ly66; CD223; LAG-3
NCBI Protein Information
lymphocyte activation gene 3 protein
UniProt Protein Name
Lymphocyte activation gene 3 protein
UniProt Gene Name
Lag3
UniProt Synonym Gene Names
LAG-3
UniProt Entry Name
LAG3_MOUSE
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Product Notes
The CD223 lag3 (Catalog #AAA49369) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's CD223 can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the CD223 lag3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD223, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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