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product-image-AAA107134_FCM15.jpg FCM/FACS (Flow Cytometry) (Staining of PMA and Ionomycin stimulated normal human peripheral blood cells with CD8a antibody and Mouse IgG1 kappa Isotype Control (PE) (left) or CD258 antibody (PE) (right). Total viable cells were used for analysis.)

Mouse CD258 Monoclonal Antibody | anti-CD258 antibody

CD258 antibody (PE)

Applications
Flow Cytometry, Functional Assay
Synonyms
CD258, Antibody; CD258 antibody (PE); Monoclonal CD258; Anti-CD258; TR2; CD 258; CD-258; CD258; HVEml; TNFSF14; LTg; anti-CD258 antibody
Ordering
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1 kappa
Clone Number
7-3
Specificity
Human
Form/Format
Liquid containing 0.09% sodium azide. May contain carrier protein/stabilizer.
Concentration
100 tests/vial (varies by lot)
Applicable Applications for anti-CD258 antibody
FCM/FACS (Flow Cytometry)
Biological Significance
This 7-3 monoclonal antibody reacts with human CD258, a 29-kDa type II transmembrane protein that is a member of the TNF ligand superfamily related to lymphotoxin-beta. Expressed on activated T cells, particularly CD8+ T cells, LIGHT plays a role in cell survival, inflammation, and tumor eradication. Furthermore, upon binding its ligand, herpesvirus entry mediator, LIGHT induces a costimulatory effect on T cells, enhancing T cell proliferation and cytokine production. LIGHT has also been shown to indirectly interact with the LT-beta receptor.
Tag/Conjugate
PE
Preparation and Storage
Store at 4°C only. Do not freeze!

FCM/FACS (Flow Cytometry)

(Staining of PMA and Ionomycin stimulated normal human peripheral blood cells with CD8a antibody and Mouse IgG1 kappa Isotype Control (PE) (left) or CD258 antibody (PE) (right). Total viable cells were used for analysis.)

product-image-AAA107134_FCM15.jpg FCM/FACS (Flow Cytometry) (Staining of PMA and Ionomycin stimulated normal human peripheral blood cells with CD8a antibody and Mouse IgG1 kappa Isotype Control (PE) (left) or CD258 antibody (PE) (right). Total viable cells were used for analysis.)
Related Product Information for anti-CD258 antibody
Mouse monoclonal CD258 antibody (PE)
Product Categories/Family for anti-CD258 antibody

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Product Notes

The CD258 (Catalog #AAA107134) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's CD258 can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the CD258 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD258, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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