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Application Data
(Human CD266 transfected cells stained with Mouse anti Human CD266:RPE)
Mouse anti-Mouse, Rat CD266 Monoclonal Antibody | anti-CD266 antibody
MOUSE ANTI HUMAN CD266
Gene Names
TNFRSF12A; FN14; CD266; TWEAKR
Reactivity
Mouse, Rat
Applications
Western Blot, Flow Cytometry, Functional Assay, Immunohistochemistry
Synonyms
CD266, Antibody; MOUSE ANTI HUMAN CD266; anti-CD266 antibody
Host
Mouse
Reactivity
Mouse, Rat
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
ITEM-4
Form/Format
Purified
Purified IgG - liquid
Purified IgG - liquid
Concentration
IgG concentration 1.0mg/ml (varies by lot)
Sequence Length
129
Applicable Applications for anti-CD266 antibody
WB (Western Blot), FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry)
Perservative Stabilisers
0.09% Sodium Azide (NaN3)
Preparation
Preparation
Immunogen
Human CD266 transfected P815 cells
Fusion Partners
Fusion Partners
Target Species
Human
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Shelf Life: 18 months from date of despatch.
Application Data
(Human CD266 transfected cells stained with Mouse anti Human CD266:RPE)
Application Data
(Human CD266 transfected cells stained with Mouse anti Human CD266:RPE)
Application Data
(Human CD266 transfected cells stained with Mouse anti Human CD266: Alexa FluorR647 (AAA50218))
Application Data
(Human CD266 transfected cells stained with Mouse anti Human CD266: Alexa FluorR647 (AAA50218))
Application Data
(Human CD266 transfected cells stained with Mouse anti Human CD266: Alexa FluorR488 (AAA50218))
Application Data
(Human CD266 transfected cells stained with Mouse anti Human CD266: Alexa FluorR488 (AAA50218))
Application Data
(Human CD266 transfected cells stained with Mouse anti Human CD266:FITC)
Application Data
(Human CD266 transfected cells stained with Mouse anti Human CD266:FITC)
Application Data
(Human CD266 transfected cells stained with Mouse anti Human CD266 (AAA50218) followed by Rabbit F(ab')2 anti Mouse IgG:RPE)
Application Data
(Human CD266 transfected cells stained with Mouse anti Human CD266 (AAA50218) followed by Rabbit F(ab')2 anti Mouse IgG:RPE)
Related Product Information for anti-CD266 antibody
Mouse anti Human CD266 antibody, clone ITEM-4 recognizes human CD266, otherwise known as Fn14/TWEAK Receptor, a 14kDa type I transmembrane glycoprotein and member of the tumour necrosis factor receptor superfamily (TNFRSF12A) expressed by a variety of tissues, including the heart, lung and kidney, and at elevated levels by human brain and liver tumours. The interaction between CD266 and its ligand CD255 (TWEAK), induces the proliferation and migration of endothelial cells and also angiogenesis, and studies have shown that CD255-induced apoptosis of some tumour cell lines is mediated by CD266 (Nakayama et al. 2003). Mouse anti Human CD266 antibody, clone ITEM-4 is cross-reactive with mouse CD266, and also with Rat-1 cells in flow cytometry.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
10,191 Da
NCBI Official Full Name
tumor necrosis factor receptor superfamily member 12A
NCBI Official Synonym Full Names
tumor necrosis factor receptor superfamily, member 12A
NCBI Official Symbol
TNFRSF12A
NCBI Official Synonym Symbols
FN14; CD266; TWEAKR
NCBI Protein Information
tumor necrosis factor receptor superfamily member 12A; FGF-inducible 14; fibroblast growth factor-inducible immediate-early response protein 14; tweak-receptor; type I transmembrane protein Fn14
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 12A
UniProt Gene Name
TNFRSF12A
UniProt Synonym Gene Names
FN14; FGF-inducible 14; TweakR
UniProt Entry Name
TNR12_HUMAN
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Product Notes
The CD266 tnfrsf12a (Catalog #AAA50218) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The MOUSE ANTI HUMAN CD266 reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CD266 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the CD266 tnfrsf12a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD266, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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