Mouse CD29 Monoclonal Antibody | anti-ITGB1 antibody

CD29 (Stem Cell Marker)

Cat. Num. AAA215385

• Gene Names: ITGB1; CD29; FNRB; MDF2; VLAB; GPIIA; MSK12; VLA-BETA
• Reactivity: Human; Does not react with Mouse or Rat
• Applications: Immunohistochemistry, ELISA
• Purity: Purified Ab with BSA and Azide at 200ug/ml or Purified Ab with BSA and Azide at 200ug/ml or Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
• Synonyms: CD29, Antibody; CD29 (Stem Cell Marker); Fibrinogen Receptor beta subunit; FNRB; Glycoprotein IIa (GPIIA); Integrin beta-1 (ITGB1); integrin VLA-4 beta subunit; MDF2; MSK12; Very Late Activation Protein beta Polypeptide; VLA-4 subunit beta; VLA-BETA; VLAB; anti-ITGB1 antibody

• Host: Mouse
• Reactivity: Human; Does not react with Mouse or Rat
• Clonality: Monoclonal
• Isotype: IgG1, kappa
• Clone Number: ITGB1/3613
• Specificity: Recognizes CD29. Binds to the cell membrane of T- and B- lymphocytes, monocytes, platelets, fibroblasts, endothelial cells, mast cells and smooth muscle cells. CD29 is an adhesion receptor and co-stimulatory molecule. This antigen was initially characterized as GPIIa on platelets and as the common b1 subunit of the very late antigen (VLA) protein family. CD29 forms a non-covalent heterodimeric complex with integrin alpha subunits. It also mediates adhesion to invasion and thrombospondin.
• Purity/Purification: Purified Ab with BSA and Azide at 200ug/ml or Purified Ab with BSA and Azide at 200ug/ml or Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
• Form/Format: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Sequence Length: 798

• Applicable Applications for anti-ITGB1 antibody: IHC (Immunohistochemistry), ELISA
• Immunogen: Purified Human beta 1 integrin from HT1080 fibrosarcoma cell extract
• Cellular Localization: Cell Surface
• Hu-chromosome Location: 10p11.2
• Positive Control: HT1080 whole cell lysate. HeLa cell line.
• Preparation and Storage: Antibody with azide: store at 2 to 8 degree C.; Antibody without azide: store at -20 to -80 degree C.; Antibody is stable for 24 months. Non-hazardous. No MSDS required.

SDS-PAGE

(SDS-PAGE Analysis Purified CD29 Mouse Monoclonal Antibody (ITGB1/3613). Confirmation of Purity and Integrity of Antibody.)

IHC (Immunohiostchemistry)

(Formalin-fixed, paraffin-embedded human kidney stained with CD29 Mouse Monoclonal Antibody (ITGB1/3613).)

IHC (Immunohistochemistry)

(Formalin-fixed, paraffin-embedded human Lung stained with CD29 Mouse Monoclonal Antibody (ITGB1/3613).)

References

Tamkun, J.W. et al. Cell 46: 271-282 (1986) | Loftus, J.C. et al. Science 249: 915-918 (1990)

NCBI and Uniprot Product Information

• NCBI GI #: 19743813
• NCBI GeneID: 3688
• NCBI Accession #: NP_002202.2
• NCBI GenBank Nucleotide #: NP_002202.2
• UniProt Accession #: P05556
• Molecular Weight: 110kDa (non-reduced); 130kDa (reduced)
• NCBI Official Full Name: integrin beta-1 isoform 1A
• NCBI Official Synonym Full Names: integrin subunit beta 1
• NCBI Official Symbol: ITGB1
• NCBI Official Synonym Symbols: CD29; FNRB; MDF2; VLAB; GPIIA; MSK12; VLA-BETA
• NCBI Protein Information: integrin beta-1
• UniProt Protein Name: Integrin beta-1
• UniProt Gene Name: ITGB1
• UniProt Synonym Gene Names: FNRB; MDF2; MSK12; GPIIA
• UniProt Entry Name: ITB1_HUMAN