Mouse CD32B Monoclonal Antibody | anti-CD32B antibody
MOUSE ANTI MOUSE CD32B: FITC
Gene Names
Fcgr2b; CD32; Fcgr2; Fcr-2; Fcr-3; Ly-17; LyM-1; Lym-1; fcRII; FcgRII; Fcgr2a; Ly-m20; AI528646; Fc[g]RII; F630109E10Rik
Applications
Flow Cytometry, Functional Assay
Synonyms
CD32B, Antibody; MOUSE ANTI MOUSE CD32B: FITC; FcRIIB, Fcgr2b, Ly-17; anti-CD32B antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
AT130-5
Specificity
Mouse anti Mouse CD32B, clone AT130-5, recognizes mouse CD32B also known as FcRIIB. CD32B (FcRIIB) is a low affinity receptor for IgG1, IgG2a and IgG2b type antibodies. Unlike other FcRs, the intracellular domain of CD32B contains a inhibitory signalling motif (ITIM) that can antagonize signal transduction mediated through other activatory receptors. FcRIIB is expressed on all myeloid populations and on B-cells.
Form/Format
Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
Sequence Length
330
Applicable Applications for anti-CD32B antibody
FCM/FACS (Flow Cytometry)
Target Species
Mouse
Preparation
Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
Preservative Stabilisers
0.09% Sodium Azide (NaN3), 1% Bovine Serum Albumin
Buffer Solution
Phosphate buffered saline
Approx. Protein Concentrations
IgG concentration 0.1 mg/ml
Immunogen
Mouse CD32-rat CD4 fusion protein
Max Ex/Em
Fluorophore: FITC
Excitation Max (nm): 490
Emission Max (nm): 525
Excitation Max (nm): 490
Emission Max (nm): 525
Fusion Partners
Spleen cells from immunized mice were fused with cells of the NS-1 myeloma cell line.
Preparation and Storage
Store at +4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Shelf Life: 18 months from date of despatch.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
Low affinity immunoglobulin gamma Fc region receptor II
NCBI Official Synonym Full Names
Fc receptor, IgG, low affinity IIb
NCBI Official Symbol
Fcgr2b
NCBI Official Synonym Symbols
CD32; Fcgr2; Fcr-2; Fcr-3; Ly-17; LyM-1; Lym-1; fcRII; FcgRII; Fcgr2a; Ly-m20; AI528646; Fc[g]RII; F630109E10Rik
NCBI Protein Information
low affinity immunoglobulin gamma Fc region receptor II-b
UniProt Protein Name
Low affinity immunoglobulin gamma Fc region receptor II
UniProt Gene Name
Fcgr2
UniProt Synonym Gene Names
Fcgr2b; Ly-17; Fc-gamma RII; Fc-gamma-RIIB; FcRII; Ly-17
UniProt Entry Name
FCGR2_MOUSE
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Product Notes
The CD32B fcgr2 (Catalog #AAA50270) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's CD32B can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the CD32B fcgr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD32B, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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