Mouse CD4 Monoclonal Antibody | anti-CD4 antibody

CD4 Antibody [8G1B12]

Cat. Num. AAA39187

• Gene Names: CD4; CD4mut
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, ELISA
• Purity: CD4 Monoclonal Antibody is immunoaffinity chromotography purified IgG.
• Synonyms: CD4, Antibody; CD4 Antibody [8G1B12]; CD4 Antibody [8G1B12] : CD4mut; CD4 molecule; anti-CD4 antibody

• Host: Mouse
• Reactivity: Human, Mouse, Rat
• Clonality: Monoclonal
• Isotype: IgG1
• Clone Number: 8G1B12
• Purity/Purification: CD4 Monoclonal Antibody is immunoaffinity chromotography purified IgG.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 458

• Applicable Applications for anti-CD4 antibody: WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: Mouse monoclonal CD4 antibody was raised against a 193 amino acid recombinant protein from near the amino terminus of human CD4.
• Buffer: CD4 Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: CD4 monoclonal antibody can be stored at -20 degree C, stable for one year.

IF (Immunofluorescence)

(Immunofluorescence of CD4 in human thymus tissue with CD4 antibody at 5 μg/ml.Green: CD4 Antibody [8G1B12]Red: Phylloidin stainingBlue: DAPI staining)

IHC (Immunohiostchemistry)

(Immunohistochemistry of CD4 in human thymus tissue with CD4 antibody at 5 μg/ml.)

WB (Western Blot)

(Western blot analysis of CD4 in rat lung tissue lysate with CD4 antibody at (A) 0.5 and (B) 1 μg/mL.)

Related Product Information for anti-CD4 antibody

CD4 Monoclonal Antibody: CD4 is a member of the immunoglobulin superfamily and is implicated as associative recognition element in MHC (Major Histocompatibility Complex) class II-restricted immune response. On T-lymphocytes, it defines the helper/inducer subset. The mature 55 kd CD4 protein consists of a 372 amino acid extracellular segment composed of four tandem immunoglobulin-like VJ regions. The CD4 molecule is a major receptor for human immunodeficiency virus (HIV), binding directly to the envelope glycoprotein gp120 on HIV, with the co-receptors being CCR5 or CXCR4. It has been shown that the V-like domains are critical for binding with HIV envelope gp120.

NCBI and Uniprot Product Information

• NCBI GI #: 10835167
• NCBI GeneID: 920
• NCBI Accession #: NP_000607
• NCBI GenBank Nucleotide #: NM_000616.4
• UniProt Accession #: P01730; Q4ZGK2; Q5U066; Q9UDE5; B2R737; D3DUS5
• Molecular Weight: 51,111 Da
• NCBI Official Full Name: T-cell surface glycoprotein CD4 isoform 1
• NCBI Official Synonym Full Names: CD4 molecule
• NCBI Official Symbol: CD4
• NCBI Official Synonym Symbols: CD4mut
• NCBI Protein Information: T-cell surface glycoprotein CD4; CD4 receptor; CD4 antigen (p55); T-cell surface antigen T4/Leu-3
• UniProt Protein Name: T-cell surface glycoprotein CD4
• UniProt Gene Name: CD4
• UniProt Entry Name: CD4_HUMAN