Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1/k
Clone Number
2B11 & PD7/26
Form/Format
CD45 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Control
Tonsil, Lymph Node
Localization
Membranous
Reactivity Note
Paraffin, Frozen
Preparation and Storage
Store at 2 to 8 degree C in the dark.
Related Product Information for anti-CD45 antibody
The CD45 antigen is a protein which was originally called Leukocyte Common Antigen. It is a Type I transmembrane protein which is in various forms present on all differentiated hematopoietic cells except erythrocytes and assists in the activation of those cells (a form of co-stimulation). It is expressed in Lymphomas, B-cell Chronic Lymphocytic Leukemia, Hairy Cell Leukemia, and Acute Non-lymphocytic Leukemia. CD45 is a monoclonal antibody that is routinely used to aid in the differential identification of undifferentiated neoplasms, whenever malignant Lymphoma is suspected by the morphological or clinical data. It is a highly specific antibody; thus, a positive result is highly indicative of lymphoid or myeloid origin. Certain types of lymphoid neoplasms may lack CD45 (Hodgkin's Disease, some T-cell Lymphomas and some Leukemias) so its absence does not rule out a hematolymphoid tumor. This antibody is exclusively expressed by cells of hematopoietic lineage and is present in most benign and malignant lymphocytes, erythrocytes and plasma cell precursors.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
139360 Da
NCBI Official Full Name
CD45
NCBI Official Symbol
ptprc
NCBI Official Synonym Symbols
PTPRc;
NCBI Protein Information
CD45
Similar Products
Product Notes
The CD45 (Catalog #AAA59190) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CD45 reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "CD45, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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