Application Data
Rat anti-Human CD45 (T200) Monoclonal Antibody | anti-CD45 (T200) antibody
Anti-Human (CD45 (T200)), Purified (clone YAML 501.4), (Rat IgG2a)
Gene Names
PTPRC; LCA; LY5; B220; CD45; L-CA; T200; CD45R; GP180
Reactivity
Human
Applications
Western Blot, Flow Cytometry, Functional Assay
Synonyms
CD45 (T200), Antibody; Anti-Human (CD45 (T200)), Purified (clone YAML 501.4), (Rat IgG2a); CD45 (T200), Purified (clone YAML 501.4), (Rat IgG2a); Anti-Human CD45 (T200) Monoclonal Antibody; anti-CD45 (T200) antibody
Host
Rat
Reactivity
Human
Clonality
Monoclonal
Isotype
Rat IgG2a
Clone Number
YAML 501.4
Specificity
(This antibody is specific for human CD45.)
Form/Format
Purifed (Purified)
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
72
Applicable Applications for anti-CD45 (T200) antibody
WB (Western Blot), FCM/FACS (Flow Cytometry)
Immunization
Rat monoclonal antibody raised against acute myeloid leukemia cells of human origin.
Presentation
Purified IgG buffered in PBS and 0.02% NaN3. (Purified from ascitic fluid via Protein G Chromatography). For maximum recovery of contents, spin down tube before use. For maximal recovery of contents, please quick-spin vial before opening.
Preparation and Storage
For all formats, store at 4 degree C. DO NOT FREEZE APC and PE conjugates. For long term storage (Purified, Biotin, FITC), aliquot and freeze unused portion at -20 degree C in volumes appropriate for single usage. Avoid freeze/thaw cycles.
Application Data
Application Data
Related Product Information for anti-CD45 (T200) antibody
anti-Human CD45 monoclonal antibody specifically binds the human CD45 Leukocyte Common Antigen (T200). CD45 is a family of single-chain transmembrane glycoproteins that consists of at least four isoforms (220, 205, 190, 180 kDa). Anti-Human CD45 monoclonal antibody recognizes an epitope common to all known isoforms. CD45 is expressed on hematopoietic cell lines, but not mature red cells, and is not detected on differentiated cells of other tissues. The protein phosphatase activity of the intracellular portion of CD45 is involved in transmembrane signaling for regulation of various cellular functions. Antibody to CD45 is used to differentiate lymphomas from nonhematopoietic undifferentiated neoplasms.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
147,254 Da
NCBI Official Full Name
CD45
NCBI Official Synonym Full Names
protein tyrosine phosphatase, receptor type, C
NCBI Official Symbol
PTPRC
NCBI Official Synonym Symbols
LCA; LY5; B220; CD45; L-CA; T200; CD45R; GP180
NCBI Protein Information
receptor-type tyrosine-protein phosphatase C; CD45 antigen; T200 glycoprotein; T200 leukocyte common antigen; protein tyrosine phosphatase, receptor type, c polypeptide
UniProt Protein Name
Receptor-type tyrosine-protein phosphatase C
UniProt Gene Name
PTPRC
UniProt Synonym Gene Names
CD45; L-CA
UniProt Entry Name
PTPRC_HUMAN
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Product Notes
The CD45 (T200) ptprc (Catalog #AAA74197) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The Anti-Human (CD45 (T200)), Purified (clone YAML 501.4), (Rat IgG2a) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD45 (T200) can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the CD45 (T200) ptprc for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD45 (T200), Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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