FCM/FACS (Flow Cytometry)
(Hela cells are stained with CD46 Monoclonal Antibody.)
Mouse anti-Human CD46 Monoclonal Antibody | anti-CD46 antibody
Mouse anti Human CD46 Antibody, Mouse MAb
Gene Names
CD46; MCP; TLX; AHUS2; MIC10; TRA2.10
Reactivity
Human
Applications
Flow Cytometry, Functional Assay, Immunofluorescence, Immunocytochemistry
Purity
Affinity purification
Synonyms
CD46, Antibody; Mouse anti Human CD46 Antibody, Mouse MAb; Membrane cofactor protein, TLX, Trophoblast leukocyte common antigen, CD46, MCP, MIC10; anti-CD46 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Purity/Purification
Affinity purification
Form/Format
0.2 um filtered solution in PBS
Sequence Length
349
Applicable Applications for anti-CD46 antibody
FCM/FACS (Flow Cytometry), IF (Immunofluorescence), ICC (Immunocytochemistry)
Immunogen
Recombinant Human CD46 protein
Preparation and Storage
Store at -20°C. Avoid freeze / thaw cycles.
FCM/FACS (Flow Cytometry)
(Hela cells are stained with CD46 Monoclonal Antibody.)
FCM/FACS (Flow Cytometry)
(Hela cells are stained with CD46 Monoclonal Antibody.)
IF (Immunofluorescence)
(Immunofluorescent analysis of Hela cells using CD46 Monoclonal Antibody at dilution of 1:50.)
IF (Immunofluorescence)
(Immunofluorescent analysis of Hela cells using CD46 Monoclonal Antibody at dilution of 1:50.)
Related Product Information for anti-CD46 antibody
CD46, also known as Membrane Cofactor Protein (MCP), is a complement regulatory protein. CD46 is a type 1 membrane protein that plays an important inhibitory role in the complement system. CD46 is expressed in white blood cells, platelets, epithelial cells, and fibroblasts. Human CD46 shares 50% amino acid sequence identity with mouse and rat CD46. The importance of CD46 to complement regulation is underscored by the observation that genetic loss of CD46 leads to development of atypical hemolytic-uremic syndrome (aHUS), a disease characterized by uncontrolled complement activation. CD46 is implicated in the development and/or progression of selected cancer types.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
44 kDa
NCBI Official Full Name
CD46
NCBI Official Synonym Full Names
CD46 molecule
NCBI Official Symbol
CD46
NCBI Official Synonym Symbols
MCP; TLX; AHUS2; MIC10; TRA2.10
NCBI Protein Information
membrane cofactor protein
UniProt Protein Name
Membrane cofactor protein
UniProt Gene Name
CD46
UniProt Synonym Gene Names
MCP; MIC10
UniProt Entry Name
MCP_HUMAN
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Product Notes
The CD46 cd46 (Catalog #AAA173451) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse anti Human CD46 Antibody, Mouse MAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD46 can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry), IF (Immunofluorescence), ICC (Immunocytochemistry). Researchers should empirically determine the suitability of the CD46 cd46 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD46, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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