Application Data
(Staining of human peripheral blood platelets with Mouse anti Human CD49b)
Mouse CD49b Monoclonal Antibody | anti-CD49b antibody
MOUSE ANTI HUMAN CD49b
Gene Names
ITGA2; BR; GPIa; CD49B; HPA-5; VLA-2; VLAA2
Reactivity
Human; Does not react with:Rat
Applications
Functional Assay, Immunofluorescence, Western Blot, Immunoprecipitation, ELISA, Immunohistochemistry, Flow Cytometry, Functional Assay
Synonyms
CD49b, Antibody; MOUSE ANTI HUMAN CD49b; INTEFRIN ALPHA 2 CHAIN, VLA-2; anti-CD49b antibody
Host
Mouse
Reactivity
Human; Does not react with:Rat
Clonality
Monoclonal
Isotype
IgG1
Clone Number
16B4
Specificity
CD49b
Form/Format
Purified
Purified IgG - liquid
Purified IgG - liquid
Concentration
IgG concentration 1.0 mg/ml (varies by lot)
Sequence Length
1181
Applicable Applications for anti-CD49b antibody
FA (Functional Assay), IF (Immunofluorescence), WB (Western Blot), IP (Immunoprecipitation), ELISA, IHC (Immunohistochemistry), FCM/FACS (Flow Cytometry)
Immunogen
Purified human beta 1 preparation from HT1080 fibrosarcoma cell extract
Perservative Stabilisers
0.09% Sodium Azide
Preparation
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Fusion Partners
Spleen cells from immunized BALB/c mice were fused with cells of the X63/Ag8.653 mouse myeloma cell line
Buffer Solution
Phosphate buffered saline
Target Species
Human
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Shelf Life: 18 months from date of despatch.
Application Data
(Staining of human peripheral blood platelets with Mouse anti Human CD49b)
Application Data
(Staining of human peripheral blood platelets with Mouse anti Human CD49b)
Related Product Information for anti-CD49b antibody
Mouse anti Human CD49b antibody, clone 16B4 recognizes human CD49b, also known as integrin alpha2, collagen receptor, Platelet membrane glycoprotein Ia or VLA-2 subunit alpha. CD49b is a 1181 amino acid ~160kDa single pass type-1 transmembrane glycoprotein posessing multiple FG-GAP repeats and a single VWFA domain. Mouse anti human CD49b antibody, clone 16B4 is identified as capable of immunoprecipitating a non-reducible alpha subunit from I125 surface labelled Human cell line extract. It is confirmed as specific to the alpha 2 subunit by relative expression of antigen on various cell lines by FACS, and its recognition of affinity purified alpha 2 beta 1 in dot blots.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
129,295 Da
NCBI Official Full Name
integrin alpha-2
NCBI Official Synonym Full Names
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
NCBI Official Symbol
ITGA2
NCBI Official Synonym Symbols
BR; GPIa; CD49B; HPA-5; VLA-2; VLAA2
NCBI Protein Information
integrin alpha-2; CD49 antigen-like family member B; VLA2 receptor, alpha-2 subunit; collagen receptor; human platelet alloantigen system 5; platelet antigen Br; platelet glycoprotein GPIa; platelet membrane glycoprotein Ia; very late activation protein 2 receptor, alpha-2 subunit
UniProt Protein Name
Integrin alpha-2
UniProt Gene Name
ITGA2
UniProt Synonym Gene Names
CD49B; GPIa
UniProt Entry Name
ITA2_HUMAN
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Product Notes
The CD49b itga2 (Catalog #AAA49629) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The MOUSE ANTI HUMAN CD49b reacts with Human; Does not react with:Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CD49b can be used in a range of immunoassay formats including, but not limited to, FA (Functional Assay), IF (Immunofluorescence), WB (Western Blot), IP (Immunoprecipitation), ELISA, IHC (Immunohistochemistry), FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the CD49b itga2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD49b, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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