IHC (Immunohiostchemistry)
(Fig: 2 Immunohistochemical analysis of CD56 in human colon ganglion using CD56 antibody (Clone: 123C3) at 1: 200 dilution.)
Mouse anti-Human CD56 Monoclonal Antibody | anti-CD56 antibody
Monoclonal Antibody to CD56 (Clone: 123C3)
Gene Names
NCAM1; CD56; NCAM; MSK39
Reactivity
Human
Applications
Flow Cytometry, Functional Assay, Immunohistochemistry
Purity
PurifiedProtein G Chromatography
Synonyms
CD56, Antibody; Monoclonal Antibody to CD56 (Clone: 123C3); NCAM1; NCAM; Neural cell adhesion molecule 1; anti-CD56 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1 Kappa
Clone Number
123C3
Purity/Purification
Purified
Protein G Chromatography
Protein G Chromatography
Form/Format
100 ug in 200 ul PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Sequence Length
848
Applicable Applications for anti-CD56 antibody
FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry)
Antigen
CD56
Immunogen Information
The immunogen for this CD56 antibody was a membrane preparation of a small cell lung carcinoma.
Conjugation
Unconjugated
Preparation and Storage
Store the antibody at 4 degree C, stable for 6 months.
For long-term storage, store at -20 degree C.
Avoid repeat freezing and thawing
For long-term storage, store at -20 degree C.
Avoid repeat freezing and thawing
IHC (Immunohiostchemistry)
(Fig: 2 Immunohistochemical analysis of CD56 in human colon ganglion using CD56 antibody (Clone: 123C3) at 1: 200 dilution.)
IHC (Immunohiostchemistry)
(Fig: 2 Immunohistochemical analysis of CD56 in human colon ganglion using CD56 antibody (Clone: 123C3) at 1: 200 dilution.)
FCM/FACS (Flow Cytometry)
(Fig: 1 Flow Cytometric analysis of hCD56 on human PBMC, lymphocytes using 1 ug/10^6 cells. Green represents isotype control; red represents anti-hCD56 antibody (10-7504). Goat anti-mouse PE conjugated secondary antibody was used.)
FCM/FACS (Flow Cytometry)
(Fig: 1 Flow Cytometric analysis of hCD56 on human PBMC, lymphocytes using 1 ug/10^6 cells. Green represents isotype control; red represents anti-hCD56 antibody (10-7504). Goat anti-mouse PE conjugated secondary antibody was used.)
Related Product Information for anti-CD56 antibody
CD56, a 175-220KDa glycoprotein, is a member of the Ig super family. It is expressed as three major isoforms and consists of five Ig-like domains and two Fibronectin-type III domains in the extracellular region. The 135kDa isoform is the basic molecule which is glycosylated or sialylated to produce the mature species. CD56 is widely expressed in nervous system, on NK cells and a specific set of Tcells. CD56+ NK cells and Tcells are unique in their ability to mediate cell-mediated cytotoxicity against certain tumor cell targets without MHC restriction. Other physiological functions of CD56 include mediating cell adhesion through homophilic and heterophilic interaction and activating intracellular signaling pathways resulting in neutrite extension and fasciculation, migration and synapses formation in brain. CD56 is also vital for neuronal development and plasticity in adult brain. It is used as a tumor marker in various cancers such as NK lymphomas and Merkel cell carcinoma. NCAM is expressed on most neuroectodermal derived lines, tissues, and neoplasms such as retinoblastoma, medulloblastoma, astrocytoma, and neuroblastoma. It is also expressed on some mesodermally derived tumors such as rhabdomyosarcoma and also on natural killer cells.
Product Categories/Family for anti-CD56 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
40,760 Da
NCBI Official Full Name
neural cell adhesion molecule 1 isoform 1
NCBI Official Synonym Full Names
neural cell adhesion molecule 1
NCBI Official Symbol
NCAM1
NCBI Official Synonym Symbols
CD56; NCAM; MSK39
NCBI Protein Information
neural cell adhesion molecule 1
UniProt Protein Name
Neural cell adhesion molecule 1
UniProt Gene Name
NCAM1
UniProt Synonym Gene Names
NCAM; N-CAM-1; NCAM-1
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Product Notes
The CD56 ncam1 (Catalog #AAA78429) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Monoclonal Antibody to CD56 (Clone: 123C3) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD56 can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the CD56 ncam1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD56, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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