FCM/FACS (Flow Cytometry)
(Staining of rat splenocytes with 0.125 ug of Mouse IgG1 kappa Isotype Control (PE) (open histogram) or 0.125 ug of CD8b antibody (PE) (filled histogram). Cells in the lymphocyte gate were used for analysis.)
Mouse anti-Human CD8b Monoclonal Antibody | anti-CD8b antibody
CD8b antibody (PE)
Gene Names
CD8B; LY3; P37; LEU2; LYT3; CD8B1
Reactivity
Human
Applications
Flow Cytometry, Functional Assay
Synonyms
CD8b, Antibody; CD8b antibody (PE); Mouse monoclonal CD8b antibody (PE); Monoclonal CD8b antibody; Anti-CD8b antibody; CD8 beta antibody; CD8b; CD-8b antibody; CD-8b; CD 8b; Ly-3 antibody; CD 8b antibody; anti-CD8b antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1 kappa
Clone Number
341
Specificity
Human
Form/Format
Supplied in aqueous buffer with 0.09% sodium azide, may contain carrier protein/stabilizer.
Concentration
200 ug/ml (varies by lot)
Sequence Length
243
Applicable Applications for anti-CD8b antibody
FCM/FACS (Flow Cytometry)
Conjugate
PE
Preparation and Storage
Store at 2-8 degree C. Do not freeze. Protect from light.
FCM/FACS (Flow Cytometry)
(Staining of rat splenocytes with 0.125 ug of Mouse IgG1 kappa Isotype Control (PE) (open histogram) or 0.125 ug of CD8b antibody (PE) (filled histogram). Cells in the lymphocyte gate were used for analysis.)
FCM/FACS (Flow Cytometry)
(Staining of rat splenocytes with 0.125 ug of Mouse IgG1 kappa Isotype Control (PE) (open histogram) or 0.125 ug of CD8b antibody (PE) (filled histogram). Cells in the lymphocyte gate were used for analysis.)
Related Product Information for anti-CD8b antibody
The 341 monoclonal antibody reacts with rat CD8beta. CD8beta is a member of the immunoglobulin superfamily which heterodimerizes with CD8 alpha to form the CD8 antigen expressed on CD4+CD8+, double-positive thymocytes, the majority of MHC class I-restricted peripheral T cells, and on some macrophages. CD8beta expression is absent in athymic mice, which are populated by T-cells expressing CD8 alpha homodimers. This has led to the idea that CD8beta expression is dependent on the development of T cells in the thymus. CD8 binds to MHC class I expressed on the surface of antigen-presenting cells during antigen presentation, and participates in T-cell receptor signal transduction through association with the kinase Lck.
Product Categories/Family for anti-CD8b antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
22,237 Da
NCBI Official Full Name
CD8b molecule
NCBI Official Synonym Full Names
CD8b molecule
NCBI Official Symbol
CD8B
NCBI Official Synonym Symbols
LY3; P37; LEU2; LYT3; CD8B1
NCBI Protein Information
T-cell surface glycoprotein CD8 beta chain
UniProt Protein Name
T-cell surface glycoprotein CD8 beta chain
UniProt Gene Name
CD8B
UniProt Synonym Gene Names
CD8B1
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Product Notes
The CD8b cd8b (Catalog #AAA224752) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CD8b antibody (PE) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD8b can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the CD8b cd8b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD8b, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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