SDS-PAGE
(SDS-PAGE Analysis Purified Cdk1 Mouse Monoclonal Antibody (A17.1.1). Confirmation of Integrity and Purity of Antibody.)
Mouse Cdk1/p34cdc2 Serine-Threonine Kinase Monoclonal Antibody | anti-Cdk1 antibody
Cdk1/p34cdc2 Serine-Threonine Kinase
Gene Names
CDK1; CDC2; CDC28A; P34CDC2
Reactivity
Human, Mouse, Rat, Guinea Pig, Woodchuck, Xenopus, Chicken. Others not known.
Applications
Immunohistochemistry, Western Blot, Immunoprecipitation, Immunofluorescence
Synonyms
Cdk1/p34cdc2 Serine-Threonine Kinase, Antibody; Cdk1/p34cdc2 Serine-Threonine Kinase; Cdc2; CDC28A; CDK1; CDKN1; CELL CYCLE CONTROLLER CDC2; Cell division control protein 2 homolog; Cell division cycle 2 G1 to S and G2 to M; Cell division protein kinase 1; Cyclin-dependent kinase 1; p34 Protein Kinase; P34CDC2; anti-Cdk1 antibody
Host
Mouse
Reactivity
Human, Mouse, Rat, Guinea Pig, Woodchuck, Xenopus, Chicken. Others not known.
Clonality
Monoclonal
Isotype
IgG2a, kappa
Clone Number
A17.1.1
Specificity
Recognizes a 34kDa protein (cdk1), identified as p34cdc2 (a catalytic subunit of Maturation Promoting Factor). Its epitope maps near the C-terminus of the protein and its core is thought to be LGTPNNEV (aa220-227 in murine cdc2). It shows no cross reaction with cdk2 p32. It supports the kinase activity. p34cdc2 plays a crucial role during cell division and is most active during mitosis. It is a serine/threonine kinase, which is activated by cyclin, by dephosphorylation of tyrosine residues. p34cdc2 is inactivated by a tyrosine kinase. This MAb reportedly inhibits the activation of p34cdc2 kinase by cyclins.
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Sequence Length
297
Applicable Applications for anti-Cdk1 antibody
IHC (Immunohistochemistry), WB (Western Blot), Kinase Assay, IP (Immunoprecipitation), IF (Immunofluorescence)
Immunogen
C-Terminal 2/3rds of Xenopus cdc2 expressed in E.coli
Cellular Localization
Nuclear and Cytoplasmic
Hu-chromosome Location
10q21.2
Positive Control
HeLa Cells or Tonsil
Preparation and Storage
Antibody with azide - store at 2 to 8 degree C.
Antibody without azide - store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Antibody without azide - store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
SDS-PAGE
(SDS-PAGE Analysis Purified Cdk1 Mouse Monoclonal Antibody (A17.1.1). Confirmation of Integrity and Purity of Antibody.)
SDS-PAGE
(SDS-PAGE Analysis Purified Cdk1 Mouse Monoclonal Antibody (A17.1.1). Confirmation of Integrity and Purity of Antibody.)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human Tonsil stained with Cdk1 Mouse Monoclonal Antibody (A17.1.1).)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human Tonsil stained with Cdk1 Mouse Monoclonal Antibody (A17.1.1).)
References
Doussis-Anagnostopoulos IA, et. al. Histopathology, 1994, 24:335-40.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
34kDa
NCBI Official Full Name
cyclin-dependent kinase 1 isoform 1
NCBI Official Synonym Full Names
cyclin dependent kinase 1
NCBI Official Symbol
CDK1
NCBI Official Synonym Symbols
CDC2; CDC28A; P34CDC2
NCBI Protein Information
cyclin-dependent kinase 1
UniProt Protein Name
Cyclin-dependent kinase 1
UniProt Gene Name
CDK1
UniProt Synonym Gene Names
CDC2; CDC28A; CDKN1; P34CDC2; CDK1
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Product Notes
The Cdk1 cdk1 (Catalog #AAA214620) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Cdk1/p34cdc2 Serine-Threonine Kinase reacts with Human, Mouse, Rat, Guinea Pig, Woodchuck, Xenopus, Chicken. Others not known. and may cross-react with other species as described in the data sheet. AAA Biotech's Cdk1/p34cdc2 Serine-Threonine Kinase can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), Kinase Assay, IP (Immunoprecipitation), IF (Immunofluorescence). Researchers should empirically determine the suitability of the Cdk1 cdk1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cdk1/p34cdc2 Serine-Threonine Kinase, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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