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product-image-AAA59287_IHC13.jpg IHC (Immunohiostchemistry) (IHC of CDK2 on an FFPE Lymphoblastic Lymphoma Tissue)

Rabbit anti-Human, Mouse CDK2 Monoclonal Antibody | anti-CDK2 antibody

CDK2 RMab

Gene Names
CDK2; CDKN2; p33(CDK2)
Reactivity
Human, Mouse
Applications
Immunohistochemistry
Synonyms
CDK2, Antibody; CDK2 RMab; anti-CDK2 antibody
Ordering
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Monoclonal
Isotype
IgG
Clone Number
RBT-CDK2
Form/Format
CDK2 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, fi lter sterilized and diluted in buff er pH 7.5, containing BSA and sodium azide as a preservative.
Sequence Length
298
Applicable Applications for anti-CDK2 antibody
IHC (Immunohistochemistry)
Localization
Nuclear
Control
Testis, Tonsil, Prostate
Intended Use
This antibody is intended for use in Immunohistochemical applications on formalinfixed paraffin-embedded tissues (FFPE), frozen tissue sections and cell preparations. Interpretation of results should be performed by a qualified medical professional.
Immunogen
A synthetic peptide corresponding to the N-terminus of the human CDK2 protein.
Preparation and Storage
Store at 2 to 8 degree C in the dark.

IHC (Immunohiostchemistry)

(IHC of CDK2 on an FFPE Lymphoblastic Lymphoma Tissue)

product-image-AAA59287_IHC13.jpg IHC (Immunohiostchemistry) (IHC of CDK2 on an FFPE Lymphoblastic Lymphoma Tissue)

Dilution Info

product-image-AAA59287_DILUTION15.jpg Dilution Info
Related Product Information for anti-CDK2 antibody
CDK2 (also known as Cyclin-dependent kinase 2 or cell division protein kinase 2) is a 33 kDa enzyme that in humans is encoded by the CDK2 gene on Chromosome 12. CDK2 is a catalytic subunit of the cyclin-dependent kinase complex, whose activity is restricted to the G1-S phase of the cell cycle, and is essential for the cellular G1/S transition.Studies indicate that over expression of CDK2 may cause the abnormal regulation of cell-cycle, which would could directly contribute to hyper-proliferation of cancerous cells. HOX genes, which play a key role in cell differentiation and morphogenisis, are regulated by CDK2. Studies have shown that HOXA7 promoted cell proliferation (mediated by cyclin E1/CDK2) is evident in cases of Hepatocellular carcinoma, indicating that CDK2 may prove to be a useful marker in such cases.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
30,035 Da
NCBI Official Full Name
cyclin-dependent kinase 2 isoform 1
NCBI Official Synonym Full Names
cyclin-dependent kinase 2
NCBI Official Symbol
CDK2
NCBI Official Synonym Symbols
CDKN2; p33(CDK2)
NCBI Protein Information
cyclin-dependent kinase 2
UniProt Protein Name
Cyclin-dependent kinase 2
UniProt Gene Name
CDK2
UniProt Synonym Gene Names
CDKN2
UniProt Entry Name
CDK2_HUMAN

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Product Notes

The CDK2 cdk2 (Catalog #AAA59287) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CDK2 RMab reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CDK2 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the CDK2 cdk2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CDK2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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