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IHC (Immunohistochemistry)
(Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CELF1 antibody. Counter stained with hematoxylin.)
Mouse anti-Human CELF1 Monoclonal Antibody | anti-CELF1 antibody
CELF1 Antibody
Gene Names
CELF1; CUGBP; NAB50; NAPOR; CUG-BP; CUGBP1; hNab50; BRUNOL2; EDEN-BP
Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Purity
Protein affinity purified
Synonyms
CELF1, Antibody; CELF1 Antibody; 50 kDa Nuclear polyadenylated RNA binding protein antibody; 50 kDa nuclear polyadenylated RNA-binding protein antibody; Bruno like 2 antibody; bruno like protein 2 antibody; Bruno-like protein 2 antibody; BRUNOL 2 antibody; BRUNOL2 antibody; CELF 1 antibody; CELF-1 antibody; celf1 antibody; CELF1 CUGBP; Elav like family member 1 antibody; CELF1_HUMAN antibody; CUG BP and ETR 3 like factor 1 antibody; CUG BP antibody; CUG BP1 antibody; CUG RNA binding protein antibody; CUG triplet repeat RNA binding protein 1 antibody; CUG triplet repeat RNA-binding protein 1 antibody; CUG-BP antibody; CUG-BP- and ETR-3-like factor 1 antibody; CUG-BP1 antibody; CUGBP 1 antibody; CUGBP and ETR3 like factor 1 antibody; CUGBP antibody; CUGBP Elav like family member 1 antibody; CUGBP Elav-like family member 1 antibody; CUGBP1 antibody; Cytidine uridine guanosine binding protein 1 antibody; Deadenylation factor CUG BP antibody; Deadenylation factor CUG-BP antibody; Deadenylation factor CUGBP antibody; EDEN BP antibody; EDEN BP homolog antibody; EDEN-BP antibody; EDEN-BP homolog antibody; embryo deadenylation element binding protein antibody; embryo deadenylation element binding protein homolog antibody; Embryo deadenylation element-binding protein homolog antibody; hNab 50 antibody; hNab50 antibody; NAB 50 antibody; NAB50 antibody; NAPOR antibody; Nuclear polyadenylated RNA binding protein 50 kD antibody; Nuclear polyadenylated RNA binding protein antibody; RNA binding protein BRUNOL 2 antibody; RNA binding protein BRUNOL2 antibody; RNA-binding protein BRUNOL-2 antibody; anti-CELF1 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Clone Number
7A1
Purity/Purification
Protein affinity purified
Form/Format
1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.
Applicable Applications for anti-CELF1 antibody
WB (Western Blot), IHC (Immunohistochemistry)
Immunogen
Recombinant protein within human CELF1 aa 1-180.
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C.
IHC (Immunohistochemistry)
(Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CELF1 antibody. Counter stained with hematoxylin.)
IHC (Immunohistochemistry)
(Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CELF1 antibody. Counter stained with hematoxylin.)
IHC (Immunohistochemisry)
(Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-CELF1 antibody. Counter stained with hematoxylin.)
IHC (Immunohistochemisry)
(Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-CELF1 antibody. Counter stained with hematoxylin.)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-CELF1 antibody. Counter stained with hematoxylin.)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-CELF1 antibody. Counter stained with hematoxylin.)
WB (Western Blot)
(Western blot analysis of CELF1 on Daudi cell lysate using anti-CELF1 antibody at 1/5, 000 dilution.)
WB (Western Blot)
(Western blot analysis of CELF1 on Daudi cell lysate using anti-CELF1 antibody at 1/5, 000 dilution.)
Related Product Information for anti-CELF1 antibody
Myotonic dystrophy (DM) is an autosomal dominant neuromuscular disease that is associated with a (CTG)n repeat expansion in the 3'-untranslated region of the myotonin protein kinase gene (DMPK). CUG-BP1 and CUG-BP2 are proteins that bind specifically to (CUG)8 oligonucleotides in vitro. While CUG-BP1 has the major binding activity in normal cells, nuclear CUG-BP2 binding activity increases in DM cells. Both CUG-BP1 and CUG-BP2 are isoforms of a novel heterogeneous nuclear ribonucleoprotein (hnRNP), hNab50. CUG-BP1, an RNA CUG triplet repeat binding protein, regulates splicing and translation of various RNAs. Expansion of RNA CUG repeats in the DMPK in DM is associated with alterations in binding activity of CUG-BP1 as well as alterations in the translation of the C/EBPb transcription factor. CUG-BP1 is an important regulator of initiation from different AUG codons of C/EBPb mRNA. In normal cells, CUG-BP1 up-regulates the p21 protein during differentiation by inducing the translation of p21 via binding to a GC-rich sequence located within the 5' region of p21 mRNA. In DM cells, failure to accumulate CUG-BP1 leads to a reduction of p21 and alterations in other proteins responsible for cell cycle withdrawl.
Product Categories/Family for anti-CELF1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
52,063 Da
NCBI Official Full Name
CUGBP Elav-like family member 1 isoform 3
NCBI Official Synonym Full Names
CUGBP, Elav-like family member 1
NCBI Official Symbol
CELF1
NCBI Official Synonym Symbols
CUGBP; NAB50; NAPOR; CUG-BP; CUGBP1; hNab50; BRUNOL2; EDEN-BP
NCBI Protein Information
CUGBP Elav-like family member 1; CELF-1; CUG-BP1; bruno-like 2; EDEN-BP homolog; bruno-like protein 2; CUG RNA-binding protein; deadenylation factor CUG-BP; RNA-binding protein BRUNOL-2; CUG-BP- and ETR-3-like factor 1; CUG triplet repeat RNA-binding prot
UniProt Protein Name
CUGBP Elav-like family member 1
UniProt Gene Name
CELF1
UniProt Synonym Gene Names
BRUNOL2; CUGBP; CUGBP1; NAB50; CELF-1; CUG-BP1
UniProt Entry Name
CELF1_HUMAN
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Product Notes
The CELF1 celf1 (Catalog #AAA312020) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CELF1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CELF1 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the CELF1 celf1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CELF1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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