Application Data
Mouse Chromogranin A Monoclonal Antibody | anti-Chga antibody
Chromogranin A
Gene Names
Chga; Chga
Reactivity
Human, Dog, Cat
Synonyms
Chromogranin A, Antibody; Chromogranin A; anti-Chga antibody
Host
Mouse
Reactivity
Human, Dog, Cat
Clonality
Monoclonal
Isotype
IgG1/K
Clone Number
LK2H10
Form/Format
Chromogranin A is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Control
Pancreas
Localization
Cytoplasmic
Reactivity Note
Paraffin, Frozen
Preparation and Storage
Store at 2 to 8°C in the dark.
Application Data
Application Data
IHC (Immunohiostchemistry)
IHC (Immunohiostchemistry)
Dilution Info
Dilution Info
Related Product Information for anti-Chga antibody
Chromogranin A is a member of the chromogranin/secretogranin family of neuroendocrine secretory pro-teins. Examples of cells producing chromogranin A are the adrenal medulla, enterochromaffin-like cells and beta cells of the pancreas. The function of chromogranin A is unknown but it is a precursor to 3 functional peptides: vasostatin, pancreastatin and parastatin. These peptides negatively modulate the neuroendocrine function of the releasing cell (autocrine) or nearby cells (paracrine). Chromogranin A is an excellent marker for Carcinoid Tumors, Pheochromocytomas, Paragangliomas, and other Neuroendocrine Tumors. Coexpression of chromogranin A and neuron-specific enolase (NSE) is common in neuroendocrine neoplasms. It has been identified in a wide variety of endocrine tissues including the pituitary, pancreas, hypothalamus, thymus, thyroid, intestine and parathyroid. It is generally accepted that the coexpression of certain keratins and chromogranin means neuroendocrine lineage. The presence of strong chromogranin staining and absence of keratin staining should raise the possibility of paraganglioma. Most pituitary adenomas and prolactinomas readily express chromogranin.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
chromogranin-A
NCBI Official Synonym Full Names
chromogranin A
NCBI Official Symbol
Chga
NCBI Official Synonym Symbols
Chga
NCBI Protein Information
chromogranin-A; cgA
UniProt Protein Name
Chromogranin-A
UniProt Gene Name
Chga
UniProt Entry Name
CMGA_MOUSE
Similar Products
Product Notes
The Chga chga (Catalog #AAA59202) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Chromogranin A reacts with Human, Dog, Cat and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "Chromogranin A, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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