IHC (Immunohiostchemistry)
(CLDN18/Claudin 18 Antibody-Human Stomach: Formalin-Fixed, Paraffin-Embedded (FFPE))
Mouse anti-Human CLDN18/Claudin 18 Monoclonal Antibody | anti-CLDN18 antibody
CLDN18/Claudin 18 Mouse anti-Human Monoclonal Antibody
Reactivity
Human
Applications
Immunohistochemistry, Immunohistochemistry
Purity
Immunogen affinity purified
Synonyms
CLDN18/Claudin 18, Antibody; CLDN18/Claudin 18 Mouse anti-Human Monoclonal Antibody; PathPlus CLDN18/Claudin 18 Antibody; CLDN18; Claudin 18; Claudin-18; SFTPJ; SFTA5; Surfactant associated 5; anti-CLDN18 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified
Form/Format
0.5% BSA, 0.1% Kathon, Tris-Buffered Saline, DI H2O and 50% glycerol
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-CLDN18 antibody
IHC (Immunohistochemistry), IHC (Immunohistochemistry)
Target
Human CLDN18/Claudin 18
Immunogen
Synthetic Claudin 18
Conjugation
Unconjugated
Family
Claudin
Preparation and Storage
Store at -20 degree C for up to 1 year.
IHC (Immunohiostchemistry)
(CLDN18/Claudin 18 Antibody-Human Stomach: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohiostchemistry)
(CLDN18/Claudin 18 Antibody-Human Stomach: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohistochemistry)
(CLDN18/Claudin 18 Antibody-Human Stomach: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohistochemistry)
(CLDN18/Claudin 18 Antibody-Human Stomach: Formalin-Fixed, Paraffin-Embedded (FFPE))
Related Product Information for anti-CLDN18 antibody
Claudin 18 antibody is an unconjugated mouse monoclonal antibody to human Claudin 18 (CLDN18). Validated for IHC.
CLDN18/claudin 18 is a member of the claudin family of integral membrane proteins that comprise tight junction strands. These are formed at points of cell-cell adhesion at the plasma membrane in epithelial cells. There are two splice variants, one expressed in the gastric mucosa and the other in lung. The gastric isoform is expressed in gastric tumors as well as tumors of other tissues, including the lung, ovary, pancreas, and esophagus. Staining is used to identify gastrointestinal and pancreatobiliary neoplasms such as gastrointestinal signet ring cell carcinoma, pancreatic ductal adenocarcinomas, and intrahepatic cholangiocarcinoma.
CLDN18/claudin 18 is a member of the claudin family of integral membrane proteins that comprise tight junction strands. These are formed at points of cell-cell adhesion at the plasma membrane in epithelial cells. There are two splice variants, one expressed in the gastric mucosa and the other in lung. The gastric isoform is expressed in gastric tumors as well as tumors of other tissues, including the lung, ovary, pancreas, and esophagus. Staining is used to identify gastrointestinal and pancreatobiliary neoplasms such as gastrointestinal signet ring cell carcinoma, pancreatic ductal adenocarcinomas, and intrahepatic cholangiocarcinoma.
References
Mol Cell Biol. 2001;21(21):7380-7390. doi: 10.1128/MCB.21.21.7380-7390.2001; Clin Cancer Res. 2008;14(23):7624-7634. doi: 10.1158/1078-0432.CCR-08-1547; Gene. 2011;481(2):83-92. doi: 10.1016/j.gene.2011.04.007; Am J Surg Pathol. 2008;32(8):1182-1189. doi: 10.1097/PAS.0b013e318163a8f8; J Histochem Cytochem. 2011;59(10):942-952. doi: 10.1369/0022155411420569; Virchows Arch. 2011;459(1):73-80. doi: 10.1007/s00428-011-1092-z.
NCBI and Uniprot Product Information
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
UniProt Protein Name
Claudin-18
UniProt Gene Name
CLDN18
UniProt Entry Name
CLD18_HUMAN
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Product Notes
The CLDN18 cldn18 (Catalog #AAA163087) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CLDN18/Claudin 18 Mouse anti-Human Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CLDN18/Claudin 18 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the CLDN18 cldn18 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CLDN18/Claudin 18, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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