Mouse cMyc Monoclonal Antibody | anti-cMyc antibody
c-Myc (9E10) Antibody
Gene Names
MYC; MRTL; MYCC; c-Myc; bHLHe39
Applications
Immunohistochemistry, Immunoprecipitation, Western Blot
Synonyms
cMyc, Antibody; c-Myc (9E10) Antibody; anti-cMyc antibody
Host
Mouse
Clonality
Monoclonal
Specificity
Detects c-Myc p67 of human origin
Form/Format
100 ug/ml of mouse monoclonal IgG1 in 1 ml PBS containing 0.1 % sodium azide and 0.2% gelatin.
Concentration
0.100 mg/ml (varies by lot)
Sequence Length
60
Applicable Applications for anti-cMyc antibody
IHC (Immunohistochemistry), IP (Immunoprecipitation), WB (Western Blot)
Origin
c-Myc (9E10) is provided mouse monoclonal IgG1 antibody, raised against a synthetic peptide corresponding to amino acids 408-439 within the carboxy terminal domain of human c-Myc.
Immunogen
Synthetic peptide corresponding to amino acids 408-439 within the carboxy terminal domain of human c-Myc.
Preparation and Storage
Store this product at 4 degree C, do not freeze. The product is stable for one year from the date of shipment.
Related Product Information for anti-cMyc antibody
The transcription factor c-Myc is a proto-oncogene that is at the focal point in cell cycle regulation, metabolism, apoptosis, differentiation, cell adhesion, and tumorigenesis (1-3). In normal cells the expression of c-Myc is tightly regulated but in human cancers c-Myc is frequently deregulated (2&3).c-Myc also plays a pivotal role in apoptosis, most notably its connections to the CD95/Fas death receptor pathway (1&4). These different biological responses to c-Myc are most likely the result of different overlapping subsets of c-Myc target genes (1).
References
1. Hoffman B, Amanullah A, Shafarenko M, Liebermann DA. 2002. The proto-oncogene c-myc in hematopoietic development and leukemogenesis. Oncogene 21(21): 3414-3421.2. Boxer LM, Dang CV. 2001. Translocations involving c-myc and c-myc function. Oncogene 20(40):5595-5610.3. Dang CV, Resar LM, Emison E, Kim S, Li Q, Prescott JE, Wonsey D, Zeller K. 1999. Function of the c-Myc oncogenic transcription factor. Exp Cell Res 253(1): 63-77.4. Prendergast GC. 1999. Mechanisms of apoptosis by c-Myc. Oncogene 18(19):2967-2987.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
7,012 Da
NCBI Official Full Name
c-myc, partial
NCBI Official Synonym Full Names
v-myc avian myelocytomatosis viral oncogene homolog
NCBI Official Symbol
MYC
NCBI Official Synonym Symbols
MRTL; MYCC; c-Myc; bHLHe39
NCBI Protein Information
myc proto-oncogene protein; avian myelocytomatosis viral oncogene homolog; class E basic helix-loop-helix protein 39; myc-related translation/localization regulatory factor; proto-oncogene c-Myc; transcription factor p64; v-myc myelocytomatosis viral oncogene homolog
UniProt Protein Name
C-myc protein
UniProt Gene Name
c-myc
UniProt Entry Name
Q6LBK7_HUMAN
Similar Products
Product Notes
The cMyc c-myc (Catalog #AAA63017) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's cMyc can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), IP (Immunoprecipitation), WB (Western Blot). Researchers should empirically determine the suitability of the cMyc c-myc for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "cMyc, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.