IHC (Immunohistochemisry)
(Immunohistochemical of Cofilin in Human lung cancer tissue using Cofilin antibody at dilution 1/2)
Cofilin Monoclonal Antibody | anti-Cofilin antibody
Cofilin Rabbit mAb
Gene Names
CFL1; CFL
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Immunocytochemistry, Immunohistochemistry, Western Blot
Purity
Affinity Purified
Synonyms
Cofilin, Antibody; Cofilin Rabbit mAb; CFL; cofilin; HEL-S-15; anti-Cofilin antibody
Host
Recombinant Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Isotype
IgG
Clone Number
S06-2C0
Purity/Purification
Affinity Purified
Form/Format
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration
0.3mg/ml (varies by lot)
Applicable Applications for anti-Cofilin antibody
IF (Immunofluorescence), ICC (Immunocytochemistry), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthetic peptide of human Cofilin
Conjugation
Unconjugated
Modification
Unmodification
Preparation and Storage
Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze/thaw cycles.
IHC (Immunohistochemisry)
(Immunohistochemical of Cofilin in Human lung cancer tissue using Cofilin antibody at dilution 1/2)
IHC (Immunohistochemisry)
(Immunohistochemical of Cofilin in Human lung cancer tissue using Cofilin antibody at dilution 1/2)
ICC (Immunocytochemistry)
(Immunocytochemistry of Cofilin (green) in hela using Cofilin Rabbit mAb at dilution 1/50, and DAPI(blue))
ICC (Immunocytochemistry)
(Immunocytochemistry of Cofilin (green) in hela using Cofilin Rabbit mAb at dilution 1/50, and DAPI(blue))
WB (Western Blot)
(Western blot detection of Cofilin in A549,MCF-7,293T cell lysates using Cofilin Rabbit mAb(1:1000 diluted).Predicted band size:19kDa.Observed band size:19kDa.)
WB (Western Blot)
(Western blot detection of Cofilin in A549,MCF-7,293T cell lysates using Cofilin Rabbit mAb(1:1000 diluted).Predicted band size:19kDa.Observed band size:19kDa.)
Related Product Information for anti-Cofilin antibody
The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004]
Product Categories/Family for anti-Cofilin antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
18,502 Da
NCBI Official Full Name
cofilin-1
NCBI Official Synonym Full Names
cofilin 1 (non-muscle)
NCBI Official Symbol
CFL1
NCBI Official Synonym Symbols
CFL
NCBI Protein Information
cofilin-1; p18; 18 kDa phosphoprotein; cofilin, non-muscle isoform
UniProt Protein Name
Cofilin-1
UniProt Gene Name
CFL1
UniProt Synonym Gene Names
CFL; p18
UniProt Entry Name
COF1_HUMAN
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Product Notes
The Cofilin cfl1 (Catalog #AAA314519) is an Antibody produced from Recombinant Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Cofilin Rabbit mAb reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Cofilin can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), ICC (Immunocytochemistry), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the Cofilin cfl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cofilin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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