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product-image-AAA120047_AD13.png Application Data

anti-Human Crizanlizumab Monoclonal Antibody | anti-SELP antibody

Research Grade Crizanlizumab

Gene Names
SELP; CD62; GRMP; PSEL; CD62P; GMP140; LECAM3; PADGEM
Reactivity
Human
Purity
>95% by SDS-PAGE. Protein A or G purified from cell culture supernatant.
Synonyms
Crizanlizumab, Antibody; Research Grade Crizanlizumab; SelG1; Leukocyte-endothelial cell adhesion molecule 3; Platelet activation dependent granule-external membrane protein; Granule membrane protein 140; GMP-140; CD62P; SELP; GRMP; PADGEM; CD62 antigen-like family member P; LECAM3; P-selectin; GMRP; anti-SELP antibody
Ordering
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2-kappa
Purity/Purification
>95% by SDS-PAGE. Protein A or G purified from cell culture supernatant.
Form/Format
Liquid; 0.01M PBS, pH 7.4
Concentration
6.06 mg/ml (varies by lot)
Expression System
XtenCHO
Host Species
Humanized
Target
Leukocyte-endothelial cell adhesion molecule 3, Platelet activation dependent granule-external membrane protein, Granule membrane protein 140, GMP-140, CD62P, SELP, GRMP, PADGEM, CD62 antigen-like family member P, LECAM3, P-selectin, GMRP
CAS
1690318-25-2
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Store at +4°C for short term (1-2 weeks).
Store at -20°C for 12 months.
Store at -80°C for long term.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Application Data

product-image-AAA120047_AD13.png Application Data

SDS-PAGE

(SDS PAGE for Crizanlizumab)

product-image-AAA120047_SDS_PAGE15.jpg SDS-PAGE (SDS PAGE for Crizanlizumab)
Product Categories/Family for anti-SELP antibody
References
Crizanlizumab: First Approval, PMID: 31933169
Effect of crizanlizumab on pain crises in subgroups of patients with sickle cell disease: A SUSTAIN study analysis, PMID: 30295335
Crizanlizumab, PMID: 32401467
Systematic Review of Crizanlizumab: A New Parenteral Option to Reduce Vaso-occlusive Pain Crises in Patients with Sickle Cell Disease, PMID: 32350885
Crizanlizumab and comparators for adults with sickle cell disease: a systematic review and network meta-analysis, PMID: 32948541

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
NCBI Official Full Name
granule membrane protein-140
NCBI Official Synonym Full Names
selectin P (granule membrane protein 140kDa, antigen CD62)
NCBI Official Symbol
SELP
NCBI Official Synonym Symbols
CD62; GRMP; PSEL; CD62P; GMP140; LECAM3; PADGEM
NCBI Protein Information
P-selectin; GMP-140; granule membrane protein 140; granulocyte membrane protein; CD62 antigen-like family member P; platelet alpha-granule membrane protein; leukocyte-endothelial cell adhesion molecule 3; platelet activation dependent granule-external mem
UniProt Protein Name
P-selectin
UniProt Gene Name
SELP
UniProt Synonym Gene Names
GMRP; GRMP; GMP-140; LECAM3; PADGEM
UniProt Entry Name
LYAM3_HUMAN

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Product Notes

The SELP selp (Catalog #AAA120047) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Research Grade Crizanlizumab reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "Crizanlizumab, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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