IHC (Immunohiostchemistry)
(Immunohistochemical analysis of CRYAB protein in paraffin embedded Adenocarcinoma of Human colon tissue using CRYAB antibody)
Mouse CRYAB Monoclonal Antibody | anti-CRYAB antibody
CRYAB antibody
Applications
Western Blot, Immunohistochemistry
Purity
CRYAB antibody was purified by affinity chromatography.
Synonyms
CRYAB, Antibody; CRYAB antibody; Monoclonal CRYAB; Anti-CRYAB; Crystallin Alpha B; CRYA2; CTPP2; HSPB5; anti-CRYAB antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
4G5
Purity/Purification
CRYAB antibody was purified by affinity chromatography.
Form/Format
Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration
500 ug-1 mg/ml (varies by lot)
Sequence Length
175
Applicable Applications for anti-CRYAB antibody
WB (Western Blot), IHC (Immunohistochemistry)
Biological Significance
Alpha crystallins are composed of: alpha-A and alpha-B, for acidic and basic, respectively. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone; instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. Alpha-A and alpha-B are differentially expressed; alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Elevated expression of alpha-B crystallin occurs in many neurological diseases; a missense mutation cosegregated in a family with a desmin-related myopathy.
Cross-Reactivity
Human
Immunogen
CRYAB antibody was raised in mouse using a protein expressed in 293T cell transfected with human CRYAB expression vector as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of CRYAB protein in paraffin embedded Adenocarcinoma of Human colon tissue using CRYAB antibody)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of CRYAB protein in paraffin embedded Adenocarcinoma of Human colon tissue using CRYAB antibody)
WB (Western Blot)
(Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant CRYAB protein (Right) or empty vector (Left) detected with CRYAB antibody)
WB (Western Blot)
(Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant CRYAB protein (Right) or empty vector (Left) detected with CRYAB antibody)
Related Product Information for anti-CRYAB antibody
Mouse monoclonal CRYAB antibody
Product Categories/Family for anti-CRYAB antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
20,129 Da
NCBI Official Full Name
CRYAB
NCBI Official Symbol
CRYAB
NCBI Protein Information
crystallin, alpha B; Alpha(B)-crystallin; Alpha-crystallin B chain
UniProt Protein Name
Alpha-crystallin B chain
UniProt Gene Name
CRYAB
UniProt Entry Name
CRYAB_PIG
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Product Notes
The CRYAB cryab (Catalog #AAA106324) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's CRYAB can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the CRYAB cryab for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CRYAB, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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