IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human kidney stained with COX-2 Recombinant Rabbit Monoclonal Antibody (COX2/3320R).)
Rabbit anti-Human Cycloxygenase-2 (COX-2) Monoclonal Antibody | anti-PTGS2 antibody
Cycloxygenase-2 (COX-2) Recombinant Rabbit Monoclonal Antibody [Clone COX2/3320R]
Gene Names
PTGS2; COX2; COX-2; PHS-2; PGG/HS; PGHS-2; hCox-2; GRIPGHS
Reactivity
Human
Applications
Immunohistochemistry
Synonyms
Cycloxygenase-2 (COX-2), Antibody; Cycloxygenase-2 (COX-2) Recombinant Rabbit Monoclonal Antibody [Clone COX2/3320R]; Glucocorticoid-regulated inflammatory Prostaglandin G/H synthase; GRIPGHS; Macrophage activation-associated marker protein P71/73; PES-2; PGG/HS; PGHS-2; Prostaglandin endoperoxide synthase 2 (PTGS2); TIS10; anti-PTGS2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
Rabbit/IgG
Clone Number
COX2/3320R
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0. 05% BSA & 0. 05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
Purified Ab with BSA and Azide at 200ug/ml
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
Applicable Applications for anti-PTGS2 antibody
IHC (Immunohistochemistry)
Antibody Type
Recombinant Antibody
Immunogen
Synthetic peptide corresponding to COX-2 residues within aa504-604 of COX-2
Cellular Localization
Cytoplasm, Cell surface
Positive Control
Human colon or lung carcinoma tissue (IHC).
Hu-chromosome Location
1q31.1
Unigene
196384
Preparation and Storage
Antibody with azide: store at 2 to 8 degree C
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human kidney stained with COX-2 Recombinant Rabbit Monoclonal Antibody (COX2/3320R).)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human kidney stained with COX-2 Recombinant Rabbit Monoclonal Antibody (COX2/3320R).)
Related Product Information for anti-PTGS2 antibody
Prostaglandins are a diverse group of autocrine and paracrine hormones that mediate many cellular and physiologic processes. Prostaglandin H2 (PGH2) is an intermediate molecule in formation of the prostaglandins. Cyclooxygenase-1 (Cox-1) and cyclooxygenase-2 (Cox-2) are prostaglandin synthases that catalyze the formation of PGH2 from arachidonic acid (AA). Cox-1 and Cox-2 are isozymes of prostaglandin-endoperoxidase synthase (PTGS). Cox-1 is constitutively expressed in most tissues and is thought to serve in general housekeeping functions. Cox-2 is efficiently induced in migratory cells responding to pro-inflammatory stimuli and is considered to be an important mediator of inflammation. Both enzymes are targets for the nonsteroidal therapeutic anti-inflammatory drugs, NSAIDs. COX2 expression is significantly increased in 85-90% of human colorectal adenocarcinomas whereas levels of COX-1 are not changed.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
68,996 Da
NCBI Official Full Name
prostaglandin G/H synthase 2
NCBI Official Synonym Full Names
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
NCBI Official Symbol
PTGS2
NCBI Official Synonym Symbols
COX2; COX-2; PHS-2; PGG/HS; PGHS-2; hCox-2; GRIPGHS
NCBI Protein Information
prostaglandin G/H synthase 2; PHS II; PGH synthase 2; cyclooxygenase 2b; prostaglandin H2 synthase 2
UniProt Protein Name
Prostaglandin G/H synthase 2
UniProt Gene Name
PTGS2
UniProt Synonym Gene Names
COX2; COX-2; PGH synthase 2; PGHS-2
UniProt Entry Name
PGH2_HUMAN
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Product Notes
The PTGS2 ptgs2 (Catalog #AAA215866) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Cycloxygenase-2 (COX-2) Recombinant Rabbit Monoclonal Antibody [Clone COX2/3320R] reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Cycloxygenase-2 (COX-2) can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the PTGS2 ptgs2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cycloxygenase-2 (COX-2), Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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