Mouse anti-Human Cystatin B Monoclonal Antibody | anti-CSTB antibody

Cystatin B (Marker of Epithelial Ovarian Cancer Progression)

Cat. Num. AAA215414

• Gene Names: CSTB; PME; ULD; CST6; EPM1; STFB; CPI-B; EPM1A
• Reactivity: Human
• Applications: Western Blot, Immunohistochemistry
• Purity: Purified Ab with BSA and Azide at 200ug/ml or Purified Ab with BSA and Azide at 200ug/ml or Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
• Synonyms: Cystatin B, Antibody; Cystatin B (Marker of Epithelial Ovarian Cancer Progression); CHROW21; CPI-B; CST 6; CSTB; CYTB; Stefin B; EPM1; Liver thiol proteinase inhibitor; PME; STFB; ULD; anti-CSTB antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG1, kappa
• Clone Number: CPTC-CSTB-3
• Specificity: Cystatin A (also designated STF1, STFA, stefin A or cystatin AS) and cystatin B (also designated PME, CST6, STFB, CPI-B, stefin B and liver thiol proteinase inhibitor) are thiol protease inhibitors that form complexes with papain and the cathepsins B, H, and L. cystatin A, a cytoplasmic protein, is one of the precursor proteins of the cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. cystatin B protects against intracellular proteases leaking out of lysosomes and is primarily expressed in heart, liver and kidney.
• Purity/Purification: Purified Ab with BSA and Azide at 200ug/ml or Purified Ab with BSA and Azide at 200ug/ml or Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
• Form/Format: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Sequence Length: 98

• Applicable Applications for anti-CSTB antibody: WB (Western Blot), IHC (Immunohistochemistry)
• Immunogen: Recombinant full-length Human Cystatin B protein
• Cellular Localization: Cytoplasmand Nucleus
• Hu-chromosome Location: 21q22.3
• Positive Control: HEK293T or U-87 MG cells. Human Tonsil.
• Preparation and Storage: Antibody with azide: store at 2 to 8 degree C.; Antibody without azide: store at -20 to -80 degree C.; Antibody is stable for 24 months. Non-hazardous. No MSDS required.

IHC (Immunohiostchemistry)

(Formalin-fixed, paraffin-embedded human lung stained with Cystatin B Mouse Monoclonal Antibody (CPTC-CSTB-3).)

SDS-PAGE

(SDS-PAGE Analysis Purified Cystatin B Mouse Monoclonal Antibody (CPTC-CSTB-3). Confirmation of Purity and Integrity of Antibody.)

References

Wang X, et al. Cystatin B is a progression marker of human epithelial ovarian tumors mediated by the TGF- signaling pathway. Int J Oncol. 2014 Apr;44(4):1099-106.

NCBI and Uniprot Product Information

• NCBI GI #: 4503117
• NCBI GeneID: 1476
• NCBI Accession #: NP_000091.1
• NCBI GenBank Nucleotide #: NP_000091.1
• UniProt Accession #: P04080
• Molecular Weight: 12kDa
• NCBI Official Full Name: cystatin-B
• NCBI Official Synonym Full Names: cystatin B
• NCBI Official Symbol: CSTB
• NCBI Official Synonym Symbols: PME; ULD; CST6; EPM1; STFB; CPI-B; EPM1A
• NCBI Protein Information: cystatin-B
• UniProt Protein Name: Cystatin-B
• UniProt Gene Name: CSTB
• UniProt Synonym Gene Names: CST6; STFB
• UniProt Entry Name: CYTB_HUMAN