IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human thyroid stained with DBC2 Mouse Monoclonal Antibody (DBC2/3364).)
Mouse anti-Human DBC2/RHOBTB2 Monoclonal Antibody | anti-RHOBTB2 antibody
DBC2/RHOBTB2 Mouse Monoclonal Antibody [Clone DBC2/3364]
Gene Names
RHOBTB2; DBC2
Reactivity
Human
Applications
Immunohistochemistry
Synonyms
DBC2/RHOBTB2, Antibody; DBC2/RHOBTB2 Mouse Monoclonal Antibody [Clone DBC2/3364]; Deleted in breast cancer 2 gene protein; p83; Rho related BTB domain containing protein 2; anti-RHOBTB2 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
Mouse/IgG2c, kappa
Clone Number
DBC2/3364
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0. 05% BSA & 0. 05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
Purified Ab with BSA and Azide at 200ug/ml
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
Applicable Applications for anti-RHOBTB2 antibody
IHC (Immunohistochemistry)
Immunogen
Human recombinant RHOBTB2 protein fragment (around aa 554-604) (exact sequence is proprietary)
Cellular Localization
Secreted in plasma
Positive Control
Human heart muscle or brain tissue.
Hu-chromosome Location
8p21.3
Unigene
372688
Preparation and Storage
Antibody with azide: store at 2 to 8 degree C
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human thyroid stained with DBC2 Mouse Monoclonal Antibody (DBC2/3364).)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human thyroid stained with DBC2 Mouse Monoclonal Antibody (DBC2/3364).)
Related Product Information for anti-RHOBTB2 antibody
The Rho subfamily of Ras-related GTPases controls multiple aspects of cell function, including cytoskeletal rearrangement, nuclear signaling and cell growth. DBC-2 (deleted in breast cancer 2 gene protein), also known as RHOBTB2 (Rho-related BTB domain-containing protein 2), is a 727 amino acid member of the RhoBTB subfamily of Rho GTPases. Members of the RhoBTB subfamily are evolutionarily conserved and are characterized by a proline-rich region, a GTPase domain and two tandem BTB repeats. Expressed ubiquitously with highest levels in neural tissue, heart, brain and fetal lung, DBC-2 contains two BTB (POZ) domains through which it may bind to and regulate the function of target proteins, such as CUL-3. Additionally, DBC-2 is thought to function as a regulator of cell cycle and apoptosis events. Under normal conditions, DBC-2 is thought to exhibit tumor suppressor activity. Mutations in the gene encoding DBC-2 are associated with breast cancer, suggesting that mutated DBC-2 may play a role in carcinogenesis.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
83,469 Da
NCBI Official Full Name
DBC2
NCBI Official Synonym Full Names
Rho-related BTB domain containing 2
NCBI Official Symbol
RHOBTB2
NCBI Official Synonym Symbols
DBC2
NCBI Protein Information
rho-related BTB domain-containing protein 2; deleted in breast cancer 2 gene protein; p83
UniProt Protein Name
Rho-related BTB domain-containing protein 2
UniProt Gene Name
RHOBTB2
UniProt Synonym Gene Names
DBC2; KIAA0717
UniProt Entry Name
RHBT2_HUMAN
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Product Notes
The RHOBTB2 rhobtb2 (Catalog #AAA215657) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The DBC2/RHOBTB2 Mouse Monoclonal Antibody [Clone DBC2/3364] reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DBC2/RHOBTB2 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the RHOBTB2 rhobtb2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DBC2/RHOBTB2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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