SDS-PAGE
(SDS-PAGE Analysis Purified DCP2 Mouse Monoclonal Antibody (PCRP-DCP2-1D6). Confirmation of Purity and Integrity of Antibody.)
Mouse DCP2 (Decapping mRNA 2) Monoclonal Antibody | anti-DCP2 antibody
DCP2 (Decapping mRNA 2) Mouse Monoclonal Antibody [Clone PCRP-DCP2-1D6]
Gene Names
DCP2; NUDT20
Reactivity
HumanPredicted to react with Mouse and Rat.
Applications
Immunofluorescence, Flow Cytometry, Functional Assay, Immunoprecipitation
Synonyms
DCP2 (Decapping mRNA 2), Antibody; DCP2 (Decapping mRNA 2) Mouse Monoclonal Antibody [Clone PCRP-DCP2-1D6]; DCP2 (Decapping mRNA 2); DCP2 decapping enzyme homolog (S. cerevisiae); DFLJ33245; hDpc; m7GpppN-mRNA hydrolase; mRNA decapping enzyme 2; nudix (nucleoside diphosphate linked moiety X)-type motif 20 (NUDT20); anti-DCP2 antibody
Host
Mouse
Reactivity
Human
Predicted to react with Mouse and Rat.
Predicted to react with Mouse and Rat.
Clonality
Monoclonal
Isotype
Mouse/IgG2a
Clone Number
PCRP-DCP2-1D6
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0. 05% BSA & 0. 05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
Purified Ab with BSA and Azide at 200ug/ml
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
Applicable Applications for anti-DCP2 antibody
IF (Immunofluorescence), FCM/FACS (Flow Cytometry), IP (Immunoprecipitation)
Immunogen
Recombinant full-length human DCP2 protein
Cellular Localization
Cytoplasm > P, body, Nucleus, Predominantly cytoplasmic, in processing bodies (PB), A minor amount is nuclear
Positive Control
MCF7, Daudi or Jurkat cells.
Hu-chromosome Location
5q22.2
Unigene
443875
Preparation and Storage
Antibody with azide: store at 2 to 8 degree C
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
SDS-PAGE
(SDS-PAGE Analysis Purified DCP2 Mouse Monoclonal Antibody (PCRP-DCP2-1D6). Confirmation of Purity and Integrity of Antibody.)
SDS-PAGE
(SDS-PAGE Analysis Purified DCP2 Mouse Monoclonal Antibody (PCRP-DCP2-1D6). Confirmation of Purity and Integrity of Antibody.)
Related Product Information for anti-DCP2 antibody
The major pathway of eukaryotic mRNA decay involves deadenylation-dependent decapping followed by 5' to 3' exonucleolytic degradation. Human decapping enzyme 2 (hDcp2) is an mRNA decapping enzyme which contains intrinsic decapping activity. In nonsense-mediated decay, the human decapping complex, made up of hDcp1 and hDcp2, may be recruited to mRNAs containing premature termination codons by nonsense-mediated decay factor (Upf) proteins. The decapping activator complex (Lsm1p-7p) is also involved in the recruitment of the decapping complex, indicated by data showing that Lsm1p-7p enhances the co-immunoprecipitation of the complex with mRNA. Dcp2 specifically hydrolyzes methylated capped RNA to release m7GDP, thereby aiding in mRNA degradation. Both Dcp1 and Dcp2 co-localize in the cytoplasm, which is consistent with their role in mRNA decay
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
46 kDa
NCBI Official Full Name
m7GpppN-mRNA hydrolase isoform 1
NCBI Official Synonym Full Names
decapping mRNA 2
NCBI Official Symbol
DCP2
NCBI Official Synonym Symbols
NUDT20
NCBI Protein Information
m7GpppN-mRNA hydrolase; hDpc; mRNA-decapping enzyme 2; DCP2 decapping enzyme homolog; nudix (nucleoside diphosphate linked moiety X)-type motif 20
UniProt Protein Name
m7GpppN-mRNA hydrolase
UniProt Gene Name
DCP2
UniProt Synonym Gene Names
NUDT20; Nudix motif 20; hDpc
UniProt Entry Name
DCP2_HUMAN
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Product Notes
The DCP2 dcp2 (Catalog #AAA215594) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The DCP2 (Decapping mRNA 2) Mouse Monoclonal Antibody [Clone PCRP-DCP2-1D6] reacts with Human Predicted to react with Mouse and Rat. and may cross-react with other species as described in the data sheet. AAA Biotech's DCP2 (Decapping mRNA 2) can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), FCM/FACS (Flow Cytometry), IP (Immunoprecipitation). Researchers should empirically determine the suitability of the DCP2 dcp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DCP2 (Decapping mRNA 2), Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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