Mouse anti-Human, Rat DCPS Monoclonal Antibody | anti-DCPS antibody

DCPS (DCS1, HINT5, m7GpppX Diphosphatase, DCS-1, Hint-related 7meGMP-directed Hydrolase, Histidine Triad Protein Member 5, Scavenger mRNA-decapping Enzyme DcpS, HSPC015)

Cat. Num. AAA14781

• Gene Names: DCPS; HINT-5
• Reactivity: Human, Rat
• Applications: ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: DCPS, Antibody; DCPS (DCS1, HINT5, m7GpppX Diphosphatase, DCS-1, Hint-related 7meGMP-directed Hydrolase, Histidine Triad Protein Member 5, Scavenger mRNA-decapping Enzyme DcpS, HSPC015); Anti -DCPS (DCS1, HINT5, m7GpppX Diphosphatase, DCS-1, Hint-related 7meGMP-directed Hydrolase, Histidine Triad Protein Member 5, Scavenger mRNA-decapping Enzyme DcpS, HSPC015); anti-DCPS antibody

• Host: Mouse
• Reactivity: Human, Rat
• Clonality: Monoclonal
• Isotype: IgG2b,k
• Clone Number: 1G4
• Specificity: Recognizes human DCPS. Species Crossreactivity: rat.
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2.
• Sequence: MADAAPQLGKRKRELDVEEAHAASTEEKEAGVGNGTCAPVRLPFSGFRLQKVLRESARDKIIFLHGKVNEASEDGDGEDAVVILEKTPFQVEQVAQLLTGSPELQLQFSNDIYSTYHLFPPRQLNDVKTTVVYPATEKHLQKYLRQDLRLIRETGDDYRNITLPHLESQSLSIQWVYNILDKKAEADRIVFENPDPSDGFVLIPDLKWNQQQLDDLYLIAICHRRGIRSLRDLTPEHLPLLRNILHQGQEAILQR

• Applicable Applications for anti-DCPS antibody: ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
• Application Notes: Suitable for use in ELISA, Western Blot, Immunohistochemistry and Immunofluorescence.; Dilution: Immunofluorescence: 10ug/ml; Immunohistochemistry (Formalin fixed paraffin embedded): 1.5ug/ml
• Immunogen: Full length recombinant corresponding to aa1-338 from human DCPS (AAH14532) with GST tag. MW of the GST tag alone is 26kD.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

WB (Western Blot)

(DCPS monoclonal antibody. Western Blot analysis of DCPS expression in PC-12.)

Application Data

(Detection limit for recombinant GST tagged DCPS is ~3ng/ml as a capture antibody.)

IF (Immunofluorescence)

(Immunofluorescence of monoclonal antibody to DCPS on HeLa cell. [antibody concentration 10ug/ml])

IHC (Immunohistochemistry)

(Immunoperoxidase of monoclonal antibody to DCPS on formalin-fixed paraffin-embedded human kidney. [antibody concentration 1.5ug/ml])

WB (Western Blot)

(DCPS monoclonal antibody Western Blot analysis of DCPS expression in HeLa.)

WB (Western Blot)

(Western Blot detection against Immunogen (63.18kD).)

Related Product Information for anti-DCPS antibody

Necessary for the complete degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA fragments shorter than 10 nucleotides that are produced by 3'->5' exosome-mediated mRNA decay. Releases m7GMP. Can also degrade m7GDP to m7GMP. Has no activity towards mRNA molecules longer than 25 nucleotides.

Product Categories/Family for anti-DCPS antibody

Antibodies; Abs to Enzymes; Phosphatase

NCBI and Uniprot Product Information

• NCBI GI #: 146186594
• NCBI GeneID: 282640
• UniProt Accession #: Q8MJJ7
• Molecular Weight: 38,402 Da
• NCBI Official Full Name: DCPS protein
• NCBI Official Synonym Full Names: decapping enzyme, scavenger
• NCBI Official Symbol: DCPS
• NCBI Official Synonym Symbols: HINT-5
• NCBI Protein Information: m7GpppX diphosphatase; DCS-1; mRNA decapping enzyme; decapping scavenger enzyme; histidine triad protein member 5; scavenger mRNA-decapping enzyme DcpS; hint-related 7meGMP-directed hydrolase; histidine triad nucleotide-binding protein 5
• UniProt Protein Name: m7GpppX diphosphatase
• UniProt Gene Name: DCPS
• UniProt Synonym Gene Names: DCS1; HINT5; HINT-5
• UniProt Entry Name: DCPS_BOVIN