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Application Data
(Staining of human peripheral blood monocytes wtih Mouse anti Human Dectin:FITC)
Mouse DECTIN-1 Monoclonal Antibody | anti-DECTIN-1 antibody
MOUSE ANTI HUMAN DECTIN-1:FITC
Gene Names
CLEC7A; BGR; CANDF4; DECTIN1; CLECSF12
Applications
Flow Cytometry, Functional Assay
Synonyms
DECTIN-1, Antibody; MOUSE ANTI HUMAN DECTIN-1:FITC; anti-DECTIN-1 antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
GE2
Form/Format
FITC
Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
Concentration
IgG concentration 0.1mg/ml (varies by lot)
Sequence Length
201
Applicable Applications for anti-DECTIN-1 antibody
FCM/FACS (Flow Cytometry)
Perservative Stabilisers
0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin
Preparation
1% Bovine Serum Albumin
Preparation
Immunogen
NIH3T3 cells expressing full length Beta-glucan receptor.
Fusion Partners
Fusion Partners
Target Species
Human
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Shelf Life: 18 months from date of despatch.
Application Data
(Staining of human peripheral blood monocytes wtih Mouse anti Human Dectin:FITC)
Application Data
(Staining of human peripheral blood monocytes wtih Mouse anti Human Dectin:FITC)
Application Data
(Staining of human peripheral blood monocytes wtih Mouse anti Human Dectin)
Application Data
(Staining of human peripheral blood monocytes wtih Mouse anti Human Dectin)
Application Data
(Staining of human peripheral blood monocytes wtih Mouse anti Human Dectin:Alexa Fluor ?488)
Application Data
(Staining of human peripheral blood monocytes wtih Mouse anti Human Dectin:Alexa Fluor ?488)
Application Data
(Staining of human peripheral blood monocytes wtih Mouse anti Human Dectin:RPE)
Application Data
(Staining of human peripheral blood monocytes wtih Mouse anti Human Dectin:RPE)
Related Product Information for anti-DECTIN-1 antibody
Mouse anti Human Dectin-1 antibody, clone GE2 recognizes human Dectin-1, also known as beta-glucan receptor (betaGR), a C-type lectin domain family member. It is a major pathogen pattern-recognition receptor that binds beta-glucans, glucose polymers that form cell-wall components or exopolymers of yeasts, fungi and some bacteria. Beta-glucans have also been used experimentally and therapeutically as immunomodulators that enhance resistance to bacterial, yeast, viral and protozoan infections, as well as tumor formation. Dectin-1 also acts as a co-stimulatory molecule on T-cells to induce their proliferation and is necessary for the TLR2-mediated inflammatory response. It is highly expressed on peripheral blood leukocytes and dendritic cells. Human Dectin-1 has two major (betaGR-A and betaGR-B) and several minor isoforms. betaGR-A and betaGR-B differs by the presence and absence, respectively, of a stalk region. Mouse anti Human Dectin-1 antibody, clone GE2recognizes both of these isoforms. Clone GE2 could be used to inhibit receptor function.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
13,138 Da
NCBI Official Full Name
C-type lectin domain family 7 member A isoform b
NCBI Official Synonym Full Names
C-type lectin domain family 7, member A
NCBI Official Symbol
CLEC7A
NCBI Official Synonym Symbols
BGR; CANDF4; DECTIN1; CLECSF12
NCBI Protein Information
C-type lectin domain family 7 member A; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12; C-type lectin superfamily member 12; DC-associated C-type lectin 1; beta-glucan receptor; dectin-1; dendritic cell-associated C-type lectin 1; dendritic cell-associated C-type lectin-1; lectin-like receptor 1
UniProt Protein Name
C-type lectin domain family 7 member A
UniProt Gene Name
CLEC7A
UniProt Synonym Gene Names
BGR; CLECSF12; DECTIN1; DC-associated C-type lectin 1; Dectin-1
UniProt Entry Name
CLC7A_HUMAN
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Product Notes
The DECTIN-1 clec7a (Catalog #AAA49772) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's DECTIN-1 can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the DECTIN-1 clec7a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DECTIN-1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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