Mouse Desmin Monoclonal Antibody | anti-DES antibody

Anti-Desmin Antibody, Mouse Monoclonal

Cat. Num. AAA254180

• Gene Names: DES; CSM1; CSM2
• Reactivity: Human; Predicted to React with: Mouse, Rat (Species predicted to react based on 100% sequence homology)
• Applications: Immunohistochemistry
• Purity: Protein A
• Synonyms: Desmin, Antibody; Anti-Desmin Antibody, Mouse Monoclonal; Desmin Antibody, Mouse MAb; desmin; Anti-CSM1 Antibody; Anti-CSM2 Antibody; Anti-LGMD2R Antibody; anti-DES antibody

• Host: Mouse
• Reactivity: Human; Predicted to React with: Mouse, Rat (Species predicted to react based on 100% sequence homology)
• Clonality: Monoclonal
• Isotype: Mouse IgG1
• Clone Number: 18
• Specificity: Human Desmin
• Purity/Purification: Protein A
• Form/Format: Liquid; 0.2um filtered solution in PBS

• Applicable Applications for anti-DES antibody: IHC (Immunohistochemistry)
• Immunogen: A synthetic peptide corresponding to the C-terminus of the Human Desmin
• Conjugation: Unconjugated
• Preparation: This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with a synthetic peptide corresponding to the C-terminus of the Human Desmin. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
• Preparation and Storage: This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.

IHC (Immunohiostchemistry)

(Immunochemical staining of human Desmin in human smooth muscle with mouse monoclonal antibody at 1:60 dilution, formalin-fixed paraffin embedded sections.)

IHC (Immunohistochemistry)

(Immunochemical staining of human Desmin in human heart with mouse monoclonal antibody at 1:60 dilution, formalin-fixed paraffin embedded sections.)

Related Product Information for anti-DES antibody

The cohesin loading factor, nipped-B-like protein (NIPBL), is also known as the sister chromatid cohesion 2 (SCC2) human homolog, is a cohesin loading factor which is essential for deposition of cohesin onto the sister chromatid. Recent studies have shown that NIPBL contributes to sister chromatid cohesion and plays a critical role in development, DNA repair, and gene regulation. Downregulation of NIPBL arrested cells in the G0/G1 phase of the cell cycle and induced apoptosis and autophagy of breast cancer cells through the caspase3 and mammalian target of rapamycin (mTOR) signaling pathways. NIPBL, the sister chromatid cohesion 2 (SCC2) human homolog, is a cohesin loading factor which is essential for deposition of cohesin onto the sister chromatid. Recent studies have shown that NIPBL contributes to sister chromatid cohesion and plays a critical role in development, DNA repair, and gene regulation.

Product Categories/Family for anti-DES antibody

Cardiac Stem Cell Markers

NCBI and Uniprot Product Information

• NCBI GI #: 55749932
• NCBI GeneID: 1674
• NCBI Accession #: NP_001918.3
• NCBI GenBank Nucleotide #: NM_001927.3
• UniProt Accession #: P17661; Q15787; Q549R7; Q549R8; Q549R9; Q8IZR1; Q8IZR6; Q8NES2; Q8NEU6; Q8TAC4; Q8TCX2; Q8TD99
• Molecular Weight: 53,536 Da
• NCBI Official Full Name: desmin
• NCBI Official Synonym Full Names: desmin
• NCBI Official Symbol: DES
• NCBI Official Synonym Symbols: CSM1; CSM2
• NCBI Protein Information: desmin; intermediate filament protein
• UniProt Protein Name: Desmin
• UniProt Gene Name: DES
• UniProt Entry Name: DESM_HUMAN