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product-image-AAA44896_WB13.jpg WB (Western Blot) (Anti-Desmin antibody (monoclonal), AAA44896, Western blottingAll lanes: Anti Desmin (AAA44896) at 0.5ug/mlLane 1: Rat Skeletal Muscle Tissue Lysate at 50ugLane 2: Rat Cardiac Muscle Tissue Lysate at 50ugLane 3: Mouse Skeletal Muscle Tissue Lysate at 50ugLane 4: Mouse Cardiac Muscle Tissue Lysate at 50ugPredicted bind size: 53KDObserved bind size: 53KD)

Mouse Desmin Monoclonal Antibody | anti-DES antibody

Anti-Desmin antibody (monoclonal)

Gene Names
DES; CSM1; CSM2; LGMD2R
Reactivity
Human, Mouse, Rat, Rabbit
Applications
Immunohistochemistry, Western Blot
Synonyms
Desmin, Antibody; Anti-Desmin antibody (monoclonal); Desmin; desmin; CMD1I; CSM1; CSM2; intermediate filament protein; anti-DES antibody
Ordering
Host
Mouse
Reactivity
Human, Mouse, Rat, Rabbit
Clonality
Monoclonal
Isotype
IgG1
Clone Number
DE-U-10
Specificity
No cross reactivity with other proteins.
Form/Format
Lyophilized
Sequence Length
470
Applicable Applications for anti-DES antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
Desmin from pig stomach.
Contents
Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
Reconstitution
Add 1mL of PBS buffer will yield a concentration of 100ug/mL
Preparation and Storage
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

WB (Western Blot)

(Anti-Desmin antibody (monoclonal), AAA44896, Western blottingAll lanes: Anti Desmin (AAA44896) at 0.5ug/mlLane 1: Rat Skeletal Muscle Tissue Lysate at 50ugLane 2: Rat Cardiac Muscle Tissue Lysate at 50ugLane 3: Mouse Skeletal Muscle Tissue Lysate at 50ugLane 4: Mouse Cardiac Muscle Tissue Lysate at 50ugPredicted bind size: 53KDObserved bind size: 53KD)

product-image-AAA44896_WB13.jpg WB (Western Blot) (Anti-Desmin antibody (monoclonal), AAA44896, Western blottingAll lanes: Anti Desmin (AAA44896) at 0.5ug/mlLane 1: Rat Skeletal Muscle Tissue Lysate at 50ugLane 2: Rat Cardiac Muscle Tissue Lysate at 50ugLane 3: Mouse Skeletal Muscle Tissue Lysate at 50ugLane 4: Mouse Cardiac Muscle Tissue Lysate at 50ugPredicted bind size: 53KDObserved bind size: 53KD)

IHC (Immunohistochemistry)

(Anti-Desmin antibody (monoclonal), AAA44896, IHC(P)IHC(P): Rat Cardiac Muscle Tissue)

product-image-AAA44896_IHC15.jpg IHC (Immunohistochemistry) (Anti-Desmin antibody (monoclonal), AAA44896, IHC(P)IHC(P): Rat Cardiac Muscle Tissue)
Related Product Information for anti-DES antibody
Background: Desmin belongs to the type III family of intermediate filaments, a class of cytoskeletal elements. DES gene encodes desmin, a muscle-specific cytoskeletal protein found in smooth, cardiac, and heart muscles. Tidball(1992) found that desmin was codistributed with actin thin filaments within the cellular processes of myotendinous junctions in frog skeletal muscle. DES gene contains 9 exons and spans about 8.4 kb. By in situ hybridization, Viegas-Pequignot et al.(1989) localized the gene to 2q35. Desmin mutation responsible for idiopathic dilated cardiomyopathy.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Official Full Name
Desmin
NCBI Official Synonym Full Names
desmin
NCBI Official Symbol
DES
NCBI Official Synonym Symbols
CSM1; CSM2; LGMD2R
NCBI Protein Information
desmin; mutant desmin p.K241E; intermediate filament protein
UniProt Protein Name
Desmin
UniProt Gene Name
DES
UniProt Entry Name
DESM_HUMAN

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Product Notes

The DES des (Catalog #AAA44896) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-Desmin antibody (monoclonal) reacts with Human, Mouse, Rat, Rabbit and may cross-react with other species as described in the data sheet. AAA Biotech's Desmin can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the DES des for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Desmin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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