IHC (Immunohistochemistry)
(IHC analysis of formalin-fixed, paraffin-embedded human uterus. Stained using rDES/1711 at 2ug/ml in PBS for 30min RT. HIER: Tris/EDTA, pH9. 0, 45min. 2 degree : HRP-polymer, 30min. DAB, 5min.)
Mouse Desmin Monoclonal Antibody | anti-DES antibody
Desmin (Muscle Cell Marker) Recombinant Mouse Monoclonal Antibody [Clone rDES/1711]
Gene Names
DES; CSM1; CSM2
Reactivity
Human, Mouse, Rat, Hamster and Chicken
Applications
Immunohistochemistry
Synonyms
Desmin, Antibody; Desmin (Muscle Cell Marker) Recombinant Mouse Monoclonal Antibody [Clone rDES/1711]; Desmin (Muscle Cell Marker); CMD1I; CSM1; CSM2; DES; Intermediate filament protein; anti-DES antibody
Host
Mouse
Reactivity
Human, Mouse, Rat, Hamster and Chicken
Clonality
Monoclonal
Isotype
Mouse/IgG1, kappa
Clone Number
rDES/1711
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0. 05% BSA & 0. 05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
Purified Ab with BSA and Azide at 200ug/ml
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
Applicable Applications for anti-DES antibody
IHC (Immunohistochemistry)
Antibody Type
Recombinant Antibody
Immunogen
Recombinant full-length human desmin protein
Cellular Localization
Cytoplasm
Positive Control
SJRH30 cells. Uterus or Leiomyosarcoma.
Hu-chromosome Location
2q35
Unigene
594952
Preparation and Storage
Antibody with azide: store at 2 to 8 degree C
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
IHC (Immunohistochemistry)
(IHC analysis of formalin-fixed, paraffin-embedded human uterus. Stained using rDES/1711 at 2ug/ml in PBS for 30min RT. HIER: Tris/EDTA, pH9. 0, 45min. 2 degree : HRP-polymer, 30min. DAB, 5min.)
IHC (Immunohistochemistry)
(IHC analysis of formalin-fixed, paraffin-embedded human uterus. Stained using rDES/1711 at 2ug/ml in PBS for 30min RT. HIER: Tris/EDTA, pH9. 0, 45min. 2 degree : HRP-polymer, 30min. DAB, 5min.)
Related Product Information for anti-DES antibody
Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. IFs are constructed from two-chain alpha-helical coiled-coil molecules arranged on an imperfect helical lattice, and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. Vimentin is an IF general marker of cells originating in the mesenchyme. Vimentin and Desmin, a related class III IF, are both expressed during skeletal muscle development. Desmin, a 469 amino acid protein found near the Z line in sarcomeres, is expressed more frequently in adult differentiated state tissues. Anti-desmin detects cells of normal smooth, skeletal, and cardiac muscles. Antibody reacts with leiomyomas, leiomyosarcoma, rhabdomyomas, rhabdomyosarcoma, and perivascular cells of glomus tumors of the skin.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
53,536 Da
NCBI Official Full Name
desmin
NCBI Official Synonym Full Names
desmin
NCBI Official Symbol
DES
NCBI Official Synonym Symbols
CSM1; CSM2
NCBI Protein Information
desmin; intermediate filament protein
UniProt Protein Name
Desmin
UniProt Gene Name
DES
UniProt Entry Name
DESM_HUMAN
Similar Products
Product Notes
The DES des (Catalog #AAA215595) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Desmin (Muscle Cell Marker) Recombinant Mouse Monoclonal Antibody [Clone rDES/1711] reacts with Human, Mouse, Rat, Hamster and Chicken and may cross-react with other species as described in the data sheet. AAA Biotech's Desmin can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the DES des for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Desmin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.