SDS-PAGE
(SDS PAGE for Dupilumab)
anti-Human Dupilumab Monoclonal Antibody | anti-IL4R antibody
Research Grade Dupilumab
Gene Names
IL4R; CD124; IL4RA; IL-4RA
Reactivity
Human
Purity
>95%; Protein A or G purified from cell culture supernatant.
Synonyms
Dupilumab, Antibody; Research Grade Dupilumab; CD124; REGN668; SAR231893; IL-4RA; IL-4-binding protein; IL-4 receptor subunit alpha; Soluble IL-4R-alpha; IL4-BP; IL4R; IL-4R subunit alpha; IL-4R-alpha; Interleukin-4 receptor subunit alpha; IL4RA; Soluble IL-4 receptor subunit alpha; sIL4Ralpha/prot; anti-IL4R antibody
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG4-kappa
Purity/Purification
>95%; Protein A or G purified from cell culture supernatant.
Form/Format
Liquid. PBS buffer, pH7.4
Concentration
1mg/ml (varies by lot)
Host Species
Human
CAS
1190264-60-8
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Store at +4 degree C short term (1-2 weeks). Store at -20 degree C 12 months. Store at -80 degree C long term.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
SDS-PAGE
(SDS PAGE for Dupilumab)
SDS-PAGE
(SDS PAGE for Dupilumab)
Bioactivity
(Detects Human CD124/IL4R in direct ELISAs.)
Bioactivity
(Detects Human CD124/IL4R in direct ELISAs.)
Product Categories/Family for anti-IL4R antibody
References
Dupilumab for treatment of atopic dermatitis, PMID: 29557246
Mechanisms of Dupilumab, PMID: 31505066
Dupilumab: A review of its use in the treatment of atopic dermatitis, PMID: 29471919
Efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps (LIBERTY NP SINUS-24 and LIBERTY NP SINUS-52): results from two multicentre, randomised, double-blind, placebo-controlled, parallel-group phase 3 trials, PMID: 31543428
Dupilumab for the treatment of asthma, PMID: 28085503
Mechanisms of Dupilumab, PMID: 31505066
Dupilumab: A review of its use in the treatment of atopic dermatitis, PMID: 29471919
Efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps (LIBERTY NP SINUS-24 and LIBERTY NP SINUS-52): results from two multicentre, randomised, double-blind, placebo-controlled, parallel-group phase 3 trials, PMID: 31543428
Dupilumab for the treatment of asthma, PMID: 28085503
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
89,658 Da
NCBI Official Full Name
interleukin-4 receptor subunit alpha isoform a
NCBI Official Synonym Full Names
interleukin 4 receptor
NCBI Official Symbol
IL4R
NCBI Official Synonym Symbols
CD124; IL4RA; IL-4RA
NCBI Protein Information
interleukin-4 receptor subunit alpha; IL4R nirs variant 1; IL-4 receptor subunit alpha; interleukin-4 receptor alpha chain
UniProt Protein Name
Interleukin-4 receptor subunit alpha
UniProt Gene Name
IL4R
UniProt Synonym Gene Names
IL4RA; IL-4 receptor subunit alpha; IL-4R subunit alpha; IL-4R-alpha; IL-4RA; Soluble IL-4 receptor subunit alpha; Soluble IL-4R-alpha; sIL4Ralpha/prot; IL4-BP
UniProt Entry Name
IL4RA_HUMAN
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Product Notes
The IL4R il4r (Catalog #AAA120062) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Research Grade Dupilumab reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "Dupilumab, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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